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論文 - 一覧

  • 26 Hits
  • 検索条件 : 絞込み (MeSH = Ubiquitin-Protein Ligases* / metabolism)
生物種 リソース名 タイトル
線虫 tm1133 , tm1968 Inactivation of SIAH-1 E3 ligase attenuates Aβ toxicity by suppressing ubiquitin-dependent DVE-1 degradation in Caenorhabditis elegans models of Alzheimer's disease.
線虫 tm1133 The Juvenile Parkinson's Disease Mutation C212Y Impairs Mitochondrial Homeostasis in a Caenorhabditis elegans Model.
ヒト・動物細胞 LNCap.FGC(RCB2144) , PC-3(RCB2145) , DU145(RCB2143) Proteomic Profiling Reveals HECTD4-dependent Regulation of Protein Ubiquitination and Signaling Pathways in Prostate Cancer.
遺伝子材料 pCAGGS (RDB08938) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) , CSII-CMV-MCS-IRES2-Bsd (RDB04385) An interactome-based framework for DDB1- and CUL4-associated factor prioritization in targeted protein degradation.
シロイヌナズナ / 植物培養細胞・遺伝子 pdi00103 CUL3LRB E3 ubiquitin ligases control thermosensory growth in Arabidopsis by differentially regulating HY5 and PIF4 protein stability.
ショウジョウバエ 12373R-1 , 7230R-2 , 8548R-3 , 3869R-1 , 3869R-2 , 4282R-3 , 12769R-2 , 4854R-2 , 9793R-1 , 11924R-2 Parkin mediates the mitochondrial dysfunction through mRpL18.
ショウジョウバエ 11321R-2 Linear ubiquitination triggers Amph-mediated T-tubule biogenesis.
遺伝子材料 IRAL022A12 (HGY088812) RNF213 Acts as a Molecular Switch for Cav-1 Ubiquitination and Phosphorylation in Human Cells.
ヒト・動物細胞 , 遺伝子材料 B16F10(RCB2630) , LNCap.FGC(RCB2144) , pCAGGS (RDB08938) In-cell proximity target validation methods for heterobifunctional molecules with CRBN- or VHL-binder using AirID.
遺伝子材料 NRCD human cDNA clone ARiS118G09 (HKR247353) Structural insights into Wnt/β-catenin signaling regulation by LGR4, R-spondin, and ZNRF3.
ヒト・動物細胞 HuH-7(RCB1366) , OS-RC-2(RCB0735) Deciphering the role of the MALT1-RC3H1 axis in regulating GPX4 protein stability.
ショウジョウバエ 10219R-3 , 6647R-1 Mitochondrial fumarate inhibits Parkin-mediated mitophagy.
線虫 tm2321 Widespread destabilization of Caenorhabditis elegans microRNAs by the E3 ubiquitin ligase EBAX-1.
線虫 tm6709 , tm1759 , tm5921 , tm6321 , tm10273 , tm2664 , tm662 HSP70 inhibits CHIP E3 ligase activity to maintain germline function in Caenorhabditis elegans.
線虫 tm2692 , tm1779 Disease-associated mutations in C-terminus of HSP70 interacting protein (CHIP) impair its ability to negatively regulate mitophagy.
ヒト・動物細胞 Huh7(RCB1366) , Huh6(RCB1367) Dual Inhibition of CDK4/6 and XPO1 Induces Senescence With Acquired Vulnerability to CRBN-Based PROTAC Drugs.
実験動物マウス RBRC01834 UBE3A controls axon initial segment in the cortical pyramidal neurons.
遺伝子材料 , ヒト・動物細胞 pMRX-IPU-muGFP-OPTN delta UBAN (RDB20078) , pMRX-IPU-muGFP-OPTN (RDB20079) , pMRX-IPU-muGFP-Ubiquitin (RDB20080) , pMRX-IPU-muGFP-p62 (RDB20081) , pMRX-IPU-muGFP-NBR1 (RDB20082) , pMRX-IPU-muGFP-NDP52 (RDB20083) , pMRX-IPU-muGFP-TAX1BP1 (RDB20084) , HeLa(RCB0007) , 293T(RCB2202) Autophagy adaptors mediate Parkin-dependent mitophagy by forming sheet-like liquid condensates.
遺伝子材料 pGL3-mUcp1Enhancer_MiniPromoter_Luciferase (RDB20463) , pGL3-mPgc1aEnhancer_MiniPromoter_Luciferase (RDB20464) , pGL3-mMtif2Promoter_Luciferase (RDB20465) Ubiquitin ligase RNF20 coordinates sequential adipose thermogenesis with brown and beige fat-specific substrates.
遺伝子材料 CSII-CMV-MCS-IRES2-Bsd (RDB04385) Polyubiquitinated PCNA triggers SLX4-mediated break-induced replication in alternative lengthening of telomeres (ALT) cancer cells.