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  • Search Condition : Filter (MeSH = beta-Thalassemia* / genetics)
Species Resource Title
Human and Animal Cells HUDEP-2(RCB4557) Upregulation of miR‑6747‑3p affects red blood cell lineage development and induces fetal hemoglobin expression by targeting BCL11A in β‑thalassemia.
Human and Animal Cells HUDEP-2(RCB4557) Editing a γ-globin repressor binding site restores fetal hemoglobin synthesis and corrects the sickle cell disease phenotype.
Human and Animal Cells HUDEP-2(RCB4557) Targeting fetal hemoglobin expression to treat β hemoglobinopathies.
Human and Animal Cells HUDEP-2(RCB4557) Correction of β-thalassemia by CRISPR/Cas9 editing of the α-globin locus in human hematopoietic stem cells.
Human and Animal Cells HUDEP-2(RCB4557) A novel gain-of-function PIP4K2A mutation elevates the expression of β-globin and aggravates the severity of α-thalassemia.
Human and Animal Cells HUDEP-2(RCB4557) Prime Editor 3 Mediated Beta-Thalassemia Mutations of the HBB Gene in Human Erythroid Progenitor Cells.
Human and Animal Cells HUDEP-2(RCB4557) Disrupting the adult globin promoter alleviates promoter competition and reactivates fetal globin gene expression.
Human and Animal Cells HUDEP-2(RCB4557) Direct correction of haemoglobin E β-thalassaemia using base editors.
Human and Animal Cells HUDEP-2(RCB4557) Base-editing-mediated dissection of a γ-globin cis-regulatory element for the therapeutic reactivation of fetal hemoglobin expression.