RRC ID |
2865
|
著者 |
Nemoto Y, Chatani M, Inohaya K, Hiraki Y, Kudo A.
|
タイトル |
Expression of marker genes during otolith development in medaka.
|
ジャーナル |
Gene Expr Patterns
|
Abstract |
Little is known about the genes and processes involved in the development of otoliths. In this study, we isolated the biomineralization-related genes otolin and chondromodulin-1 (chm1) from medaka, and examined their spatiotemporal expression pattern as well as that of two other genes also related to biomineralization, i.e., sparc/osteonectin and type II collagen (col2a), during otic development in medaka. Our results demonstrated that all the tested genes were expressed in the otic vesicle, and that chm1 was exclusively expressed in the semicircular canal of the otic vesicle.
|
巻・号 |
8(2)
|
ページ |
92-5
|
公開日 |
2008-1-1
|
DOI |
10.1016/j.modgep.2007.10.001
|
PII |
S1567-133X(07)00096-8
|
PMID |
17981516
|
MeSH |
Animals
Biomarkers*
Collagen Type II / genetics
Embryo, Nonmammalian
Extracellular Matrix Proteins / genetics
Gene Expression Regulation, Developmental*
Membrane Proteins / genetics
Organogenesis
Oryzias / embryology*
Oryzias / genetics*
Osteonectin / genetics
Otolithic Membrane / embryology*
Semicircular Canals / embryology
Semicircular Canals / metabolism
|
IF |
0.897
|
引用数 |
12
|
WOS 分野
|
GENETICS & HEREDITY
DEVELOPMENTAL BIOLOGY
|
リソース情報 |
メダカ |
Cab
an inbred wild-type strain |