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Reference Info.
Pubmed ID 27606946  
RRC ID 47635 
Author Ohbuchi K, Mori Y, Ogawa K, Warabi E, Yamamoto M, Hirokawa T. 
Title Detailed Analysis of the Binding Mode of Vanilloids to Transient Receptor Potential Vanilloid Type I (TRPV1) by a Mutational and Computational Study. 
Journal PLoS ONE 
Published 2016-9-9 
Volume 11(9) 
Pages e0162543 
DOI 10.1371/journal.pone.0162543   
PII PONE-D-16-20075 
MeSH
Amino Acids / chemistry
Calcium / metabolism
Capsaicin / chemistry
Capsaicin / pharmacology
Catechols / chemistry
Catechols / pharmacology
DNA Mutational Analysis
Diterpenes / chemistry
Diterpenes / pharmacology
Fatty Alcohols / chemistry
Fatty Alcohols / pharmacology
Humans
Kinetics
Ligands
Models, Molecular*
Molecular Docking Simulation
Mutant Proteins / chemistry
Mutant Proteins / metabolism
Mutation / genetics*
Point Mutation / genetics
Protons
Reproducibility of Results
Sequence Homology, Amino Acid
Structure-Activity Relationship
TRPV Cation Channels / agonists*
TRPV Cation Channels / chemistry
TRPV Cation Channels / genetics*
Resource Info.
Species DNA material 
Resource name
pcDNA3.1-hTRPV1-FLAG WT (RDB14587), pcDNA3.1-hTRPV1-FLAG-C158A (RDB14588), pcDNA3.1-hTRPV1-FLAG-L515A (RDB14589), pcDNA3.1-hTRPV1-FLAG-L518A (RDB14590), pcDNA3.1-hTRPV1-FLAG-L547A (RDB14591), pcDNA3.1-hTRPV1-FLAG-T550A (RDB14592), pcDNA3.1-hTRPV1-FLAG-I573A (RDB14593), pcDNA3.1-hTRPV1-FLAG-F587A (RDB14594), pcDNA3.1-hTRPV1-FLAG-F591A (RDB14595), pcDNA3.1-hTRPV1-FLAG-L670A (RDB14596), pcDNA3.1-hTRPV1-FLAG-S512A (RDB14597), pcDNA3.1-hTRPV1-FLAG-Y511F (RDB14598). 

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