論文 - 詳細
RRC ID | 1093 |
---|---|
著者 | Okamoto S, Hosoe T, Itabashi T, Nozawa K, Okada K, Takaki GM, Chikamori M, Yaguchi T, Fukushima K, Miyaji M, Kawai K. |
タイトル | New decalin derivatives, eujavanoic acids A and B, from Eupenicillium javanicum. |
ジャーナル | J Nat Prod |
Abstract |
Two new decalin derivatives, eujavanoic acids A (1) and B (2), were isolated from Eupenicillium javanicum, along with several compactin derivatives. The structures of 1 and 2 were determined by spectroscopic methods and modified Mosher's method. The side chain (2-methylbutanoyloxy) and acid functionalities of compactin derivatives were necessary to show the antifungal activity. |
巻・号 | 67(9) |
ページ | 1580-3 |
公開日 | 2004-9-1 |
DOI | 10.1021/np040052s |
PMID | 15387665 |
MeSH | Antifungal Agents / chemistry Antifungal Agents / isolation & purification* Antifungal Agents / pharmacology Ascomycota / chemistry* Aspergillus fumigatus / drug effects Candida albicans / drug effects Cryptococcus neoformans / drug effects Lovastatin / analogs & derivatives* Lovastatin / chemistry Lovastatin / pharmacology Molecular Conformation Molecular Structure Naphthalenes / chemistry Naphthalenes / isolation & purification* Naphthalenes / pharmacology |
IF | 3.782 |
引用数 | 6 |
WOS 分野 | PLANT SCIENCES PHARMACOLOGY & PHARMACY CHEMISTRY, MEDICINAL |
リソース情報 | |
病原微生物 | E. javanicum? IFM 52670 |