論文 - 詳細
| RRC ID | 11268 |
|---|---|
| 著者 | Kidokoro K, Ito K, Ogoyi DO, Abe H, Mita K, Kadono-Okuda K. |
| タイトル | Non-susceptibility genes to Bombyx densovirus type 1, Nid-1 and nsd-1, affect distinct steps of the viral infection pathway. |
| ジャーナル | J Invertebr Pathol |
| Abstract |
In the silkworm Bombyx mori, densovirus type 1 (BmDNV-1) replicates only in the midgut and causes fatal disease. Resistance to BmDNV-1 is determined by two genes, nsd-1 and Nid-1, respectively. Neither of them has been identified yet. We investigated the viral transcript by RT-PCR in inoculated silkworms carrying different sets of nsd-1 and Nid-1 genotype. BmDNV-1 transcript was not detected in nsd-1-carrying strains irrespective of existence of Nid-1 but clearly detected in strains carrying Nid-1 without nsd-1. The result suggests that nsd-1 blocks early step of infection. On the other hand, Nid-1 does not block cell and nucleus entry and viral transcription in nuclei but blocks later step in the viral infection cycle. |
| 巻・号 | 103(1) |
| ページ | 79-81 |
| 公開日 | 2010-1-1 |
| DOI | 10.1016/j.jip.2009.10.006 |
| PII | S0022-2011(09)00217-1 |
| PMID | 19836396 |
| MeSH | Animals Bombyx / genetics* Bombyx / virology* Densovirus / pathogenicity* Digestive System / virology Genes, Insect* Genetic Predisposition to Disease / genetics* Genotype Insect Viruses / pathogenicity |
| IF | 2.074 |
| 引用数 | 9 |
| WOS 分野 | ZOOLOGY |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 各媒体での言及数の合計 | 0 |
| リソース情報 | |
| カイコ | n30 |