Reference - Detail
| RRC ID | 11516 |
|---|---|
| Author | Nakashimada Y, Michinaka A, Watanabe K, Nishio N, Fujii T. |
| Title | Brewer's yeast cell wall affects microbiota composition and decreases Bacteroides fragilis populations in an anaerobic gut intestinal model. |
| Journal | J Biosci Bioeng |
| Abstract |
Brewer's yeast cell wall (BYC) has been reported to have prebiotic activity that improves the microbiotal composition of the human gut. To understand the precise effect of BYC on gut microbiota and its metabolism, we used a three-stage continuous-flow reactor system that mimicked the environment of the large intestine. The reactor system was able to maintain the bacterial community stably for a week. The Bacteroides fragilis population decreased drastically after the addition of BYC into this system while the number of Lactobacillus was stably maintained. In addition, propionate and acetate levels increased drastically. This metabolic change correlated with an increase in a number of specific operational taxonomic units annotated to the genus Veillonella and Megasphaella. These results suggest that BYC affects the composition of microbiota in an in vitro model system. |
| Volume | 111(2) |
| Pages | 178-84 |
| Published | 2011-2-1 |
| DOI | 10.1016/j.jbiosc.2010.09.005 |
| PII | S1389-1723(10)00314-2 |
| PMID | 20926339 |
| MeSH | Animals Bacteroides fragilis / genetics Bacteroides fragilis / growth & development* Carbohydrate Metabolism Cell Wall / chemistry* DNA, Bacterial / analysis Feces / microbiology Fermentation Intestine, Large / microbiology Lactobacillus / genetics Lactobacillus / growth & development Metagenome* Polymorphism, Restriction Fragment Length Saccharomyces cerevisiae / growth & development* Swine |
| IF | 2.366 |
| Times Cited | 5 |
| WOS Category | FOOD SCIENCE & TECHNOLOGY BIOTECHNOLOGY & APPLIED MICROBIOLOGY |
| Resource | |
| General Microbes | JCM 1149 JCM 5826 JCM 10188 JCM 1471 |