Reference - Detail
| RRC ID | 1154 |
|---|---|
| Author | Chibana H, Uno J, Cho T, Mikami Y. |
| Title | Mutation in IRO1 tightly linked with URA3 gene reduces virulence of Candida albicans. |
| Journal | Microbiol Immunol |
| Abstract |
Gene deletion in the pathogenic fungus Candida albicans has relied heavily on a URA3 cassette and a recipient delta ura3 strain CAI4. The IRO1 gene adjacent to URA3 was inadvertently deleted during construction of CAI4. We report here that a mutation in IRO1 reduces virulence of C. albicans. |
| Volume | 49(10) |
| Pages | 937-9 |
| Published | 2005-1-1 |
| DOI | 10.1111/j.1348-0421.2005.tb03686.x |
| PII | JST.JSTAGE/mandi/49.937 |
| PMID | 16237272 |
| MeSH | Animals Candida albicans / growth & development Candida albicans / pathogenicity* Candidiasis / microbiology Disease Models, Animal Fungal Proteins / genetics* Fungal Proteins / physiology Gene Deletion Mice Mice, Inbred BALB C Mutation Survival Analysis Transcription Factors / genetics* Transcription Factors / physiology Virulence / genetics* |
| IF | 1.566 |
| Times Cited | 13 |
| WOS Category | IMMUNOLOGY MICROBIOLOGY |
| Resource | |
| Pathogenic microorganisms | IFM 46932 C. albicans? |