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Species Resource Title
Human and Animal Cells Ba/F3-CL-1 (RCB4474) Targeting anaplastic lymphoma kinase (ALK) gene alterations in neuroblastoma by using alkylating pyrrole-imidazole polyamides.
Human and Animal Cells HeLa(RCB0007) , REF-RGB(RCB0165) HeLa ZIP kinase induces diphosphorylation of myosin II regulatory light chain and reorganization of actin filaments in nonmuscle cells.
Drosophila Refinement of wingless expression by a wingless- and notch-responsive homeodomain protein, defective proventriculus.
DNA material pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) Long-term expression of the lamin A mutant associated with dilated cardiomyopathy induces senescence.
Human and Animal Cells Ba/F3(RCB0805) Mutations in G protein β subunits promote transformation and kinase inhibitor resistance.
Human and Animal Cells MKN45(RCB1001) 5‑FU resistance abrogates the amplified cytotoxic effects induced by inhibiting checkpoint kinase 1 in p53‑mutated colon cancer cells.
Prokaryotes E. coli The Di-iron RIC Protein (YtfE) of Escherichia coli Interacts with the DNA-Binding Protein from Starved Cells (Dps) To Diminish RIC Protein-Mediated Redox Stress.
Prokaryotes E. coli Novel mechanisms of TolC-independent decreased bile-salt susceptibility in Escherichia coli.
Arabidopsis / Cultured plant cells, genes pda TRIPP Is a Plant-Specific Component of the Arabidopsis TRAPPII Membrane Trafficking Complex with Important Roles in Plant Development.
Silkworms Large-Scale Screening and Identification of Novel Pathogenic Staphylococcus aureus Genes Using a Silkworm Infection Model.
Zebrafish Tg(isl1:GFP) rw0 , Tg(vglut2a:loxP-DsRed-loxP-GFP) Glycine decarboxylase deficiency-induced motor dysfunction in zebrafish is rescued by counterbalancing glycine synaptic level.
Zebrafish spns2 Development and growth of organs in living whole embryo and larval grafts in zebrafish.
C.elegans tm1200 , tm872 , tm1231 , tm1489 , tm876 Germ granule dysfunction is a hallmark and mirror of Piwi mutant sterility.
Human and Animal Cells MG6(RCB2403) Progranulin regulates lysosomal function and biogenesis through acidification of lysosomes.
Human and Animal Cells LY-B(RCB1698) Toxoplasma gondii salvages sphingolipids from the host Golgi through the rerouting of selected Rab vesicles to the parasitophorous vacuole.
Human and Animal Cells PC-9(RCB4455) Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Oncogenic EGFR Mutants with Selectivity over Wild-Type EGFR.
Human and Animal Cells PC-9(RCB4455) Discovery of 1-{(3R,4R)-3-[({5-Chloro-2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)methyl]-4-methoxypyrrolidin-1-yl}prop-2-en-1-one (PF-06459988), a Potent, WT Sparing, Irreversible Inhibitor of T790M-Containing EGFR Mutants.
Human and Animal Cells TE-8(RCB2098) , TE-10(RCB2099) Targeting p300 Addiction in CBP-Deficient Cancers Causes Synthetic Lethality by Apoptotic Cell Death due to Abrogation of MYC Expression.
Human and Animal Cells COS-7(RCB0539) Structure of IZUMO1-JUNO reveals sperm-oocyte recognition during mammalian fertilization.
Zebrafish RIKEN WT IMU1003, an atrarate derivative, inhibits Wnt/β-catenin signaling.