論文 - 詳細
| RRC ID | 11555 |
|---|---|
| 著者 | Nozawa M, Aotsuka T, Tamura K. |
| タイトル | A novel chimeric gene, siren, with retroposed promoter sequence in the Drosophila bipectinata complex. |
| ジャーナル | Genetics |
| Abstract |
Retrotransposons often produce a copy of host genes by their reverse transcriptase activity operating on host gene transcripts. Since transcripts normally do not contain promoter, a retroposed gene copy usually becomes a retropseudogene. However, in Drosophila bipectinata and a closely related species we found a new chimeric gene, whose promoter was likely produced by retroposition. This chimeric gene, named siren, consists of a tandem duplicate of Adh and a retroposed fragment of CG11779 containing the promoter and a partial intron in addition to the first exon. We found that this unusual structure of a retroposed fragment was obtained by retroposition of nanos, which overlaps with CG11779 on the complementary strand. The potential of retroposition to produce a copy of promoter and intron sequences in the context of gene overlapping was demonstrated. |
| 巻・号 | 171(4) |
| ページ | 1719-27 |
| 公開日 | 2005-12-1 |
| DOI | 10.1534/genetics.105.041699 |
| PII | genetics.105.041699 |
| PMID | 16143626 |
| PMC | PMC1456098 |
| MeSH | Alcohol Dehydrogenase Alcohol Oxidoreductases / genetics Amino Acid Sequence Animals Base Sequence Cloning, Molecular Drosophila / genetics* Drosophila Proteins / genetics Evolution, Molecular* Genetic Linkage Models, Genetic Molecular Sequence Data Mutant Chimeric Proteins / genetics* Phylogeny Promoter Regions, Genetic / genetics* RNA-Binding Proteins / genetics Retroelements / genetics* Reverse Transcriptase Polymerase Chain Reaction Sequence Analysis, DNA |
| IF | 4.015 |
| 引用数 | 16 |
| WOS 分野 | GENETICS & HEREDITY |
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| 最多言及媒体 | F1000Research |
| 各媒体での言及数の合計 | 1 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
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