RRC ID 11660
著者 Ichikawa A, Yamada A, Sakamoto H, Umehara M, Yoshioka Y, Yamaguchi M, Ikura K.
タイトル Overexpression of transglutaminase in the Drosophila wing imaginal disc induced an extra wing crossvein phenotype.
ジャーナル Biosci Biotechnol Biochem
Abstract To determine the roles of Drosophila transglutaminase-A (dTG-A), we examined a phenotype induced through ectopic expression of dTG-A. Overexpression of dTG-A in the wing imaginal disc induced an extra wing crossvein phenotype. This phenotype was suppressed by crossing with epidermal growth factor receptor (Egfr) signaling pathway mutant flies. These results indicate that this phenotype, induced by dTG-A, is related to enhancement of the Egfr signaling pathway.
巻・号 74(12)
ページ 2494-6
公開日 2010-12-7
DOI 10.1271/bbb.100449
PII JST.JSTAGE/bbb/100449
PMID 21150110
MeSH Animals Drosophila melanogaster / anatomy & histology* Drosophila melanogaster / enzymology* Drosophila melanogaster / genetics Gene Expression Phenotype* Transglutaminases / genetics* Wings, Animal / anatomy & histology* Wings, Animal / enzymology*
IF 1.516
引用数 5
WOS 分野 FOOD SCIENCE & TECHNOLOGY CHEMISTRY, APPLIED BIOTECHNOLOGY & APPLIED MICROBIOLOGY BIOCHEMISTRY & MOLECULAR BIOLOGY
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