RRC ID 1167
著者 Hattori N, Shirai A, Sugiura Y, Li W, Yokoyama K, Misawa Y, Okuzumi K, Tamaki K.
タイトル Onychomycosis caused by Fusarium proliferatum.
ジャーナル Br J Dermatol
Abstract Fusarium infections in humans are usually opportunistic, but the fungus sometimes infects healthy persons, causing keratomycosis or onychomycosis. Onychomycosis is usually caused by F. solani or F. oxysporum. We report the first two cases of onychomycosis caused by F. proliferatum, and discuss methods of diagnosis and effective treatment. Nail samples from the two patients were examined by direct microscopy, cultured, and identified morphologically and genetically as F. proliferatum. Both patients were treated successfully with oral itraconazole, even though the minimum inhibitory concentration of itraconazole was relatively high in Patient 1. This is the first report of F. proliferatum as an agent of onychomycosis. Itraconazole may be effective in the treatment of onychomycosis caused by F. proliferatum.
巻・号 153(3)
ページ 647-9
公開日 2005-9-1
DOI 10.1111/j.1365-2133.2005.06692.x
PII BJD6692
PMID 16120158
MeSH Antifungal Agents / therapeutic use Foot Dermatoses / drug therapy Foot Dermatoses / microbiology* Fusarium* / genetics Genes, Fungal Hand Dermatoses / drug therapy Hand Dermatoses / microbiology* Humans Itraconazole / therapeutic use Japan Male Middle Aged Onychomycosis / drug therapy Onychomycosis / microbiology* Pulse Therapy, Drug Sequence Analysis, DNA
IF 7.0
引用数 20
WOS 分野 DERMATOLOGY
リソース情報
病原微生物 F. solani? F. oxysporum? F. proliferatum?