| RRC ID |
12118
|
| 著者 |
Wada H, Ghysen A, Satou C, Higashijima S, Kawakami K, Hamaguchi S, Sakaizumi M.
|
| タイトル |
Dermal morphogenesis controls lateral line patterning during postembryonic development of teleost fish.
|
| ジャーナル |
Dev Biol
|
| Abstract |
The lateral line system displays highly divergent patterns in adult teleost fish. The mechanisms underlying this variability are poorly understood. Here, we demonstrate that the lateral line mechanoreceptor, the neuromast, gives rise to a series of accessory neuromasts by a serial budding process during postembryonic development in zebrafish. We also show that accessory neuromast formation is highly correlated to the development of underlying dermal structures such as bones and scales. Abnormalities in opercular bone morphogenesis, in endothelin 1-knockdown embryos, are accompanied by stereotypic errors in neuromast budding and positioning, further demonstrating the tight correlation between the patterning of neuromasts and of the underlying dermal bones. In medaka, where scales form between peridermis and opercular bones, the lateral line displays a scale-specific pattern which is never observed in zebrafish. These results strongly suggest a control of postembryonic neuromast patterns by underlying dermal structures. This dermal control may explain some aspects of the evolution of lateral line patterns.
|
| 巻・号 |
340(2)
|
| ページ |
583-94
|
| 公開日 |
2010-4-15
|
| DOI |
10.1016/j.ydbio.2010.02.017
|
| PII |
S0012-1606(10)00102-8
|
| PMID |
20171200
|
| MeSH |
Animals
Animals, Genetically Modified
Body Patterning*
Bone and Bones / embryology
Dermis / cytology
Dermis / growth & development
Embryo, Nonmammalian
Immunohistochemistry
In Situ Hybridization
Lateral Line System / cytology
Lateral Line System / growth & development*
Mechanoreceptors / cytology
Microinjections
Microscopy, Video
Models, Biological
Morphogenesis*
Oligonucleotides, Antisense / metabolism
Oryzias / embryology
Oryzias / growth & development*
Species Specificity
Zebrafish / embryology
Zebrafish / growth & development*
|
| IF |
2.896
|
| 引用数 |
41
|
|
WOS 分野
|
DEVELOPMENTAL BIOLOGY
|
| リソース情報 |
| ゼブラフィッシュ |
rw0(Tg(CM-isl1:GFP))
HGn39D
HG21C
Tg(UAS:GFP) |
