RRC ID 12118
Author Wada H, Ghysen A, Satou C, Higashijima S, Kawakami K, Hamaguchi S, Sakaizumi M.
Title Dermal morphogenesis controls lateral line patterning during postembryonic development of teleost fish.
Journal Dev. Biol.
Abstract The lateral line system displays highly divergent patterns in adult teleost fish. The mechanisms underlying this variability are poorly understood. Here, we demonstrate that the lateral line mechanoreceptor, the neuromast, gives rise to a series of accessory neuromasts by a serial budding process during postembryonic development in zebrafish. We also show that accessory neuromast formation is highly correlated to the development of underlying dermal structures such as bones and scales. Abnormalities in opercular bone morphogenesis, in endothelin 1-knockdown embryos, are accompanied by stereotypic errors in neuromast budding and positioning, further demonstrating the tight correlation between the patterning of neuromasts and of the underlying dermal bones. In medaka, where scales form between peridermis and opercular bones, the lateral line displays a scale-specific pattern which is never observed in zebrafish. These results strongly suggest a control of postembryonic neuromast patterns by underlying dermal structures. This dermal control may explain some aspects of the evolution of lateral line patterns.
Volume 340(2)
Pages 583-94
Published 2010-4-15
DOI 10.1016/j.ydbio.2010.02.017
PII S0012-1606(10)00102-8
PMID 20171200
MeSH Animals Animals, Genetically Modified Body Patterning* Bone and Bones / embryology Dermis / cytology Dermis / growth & development Embryo, Nonmammalian Immunohistochemistry In Situ Hybridization Lateral Line System / cytology Lateral Line System / growth & development* Mechanoreceptors / cytology Microinjections Microscopy, Video Models, Biological Morphogenesis* Oligonucleotides, Antisense / metabolism Oryzias / embryology Oryzias / growth & development* Species Specificity Zebrafish / embryology Zebrafish / growth & development*
IF 3.262
Times Cited 27
WOS Category DEVELOPMENTAL BIOLOGY
Resource
Zebrafish rw0(Tg(CM-isl1:GFP)) HGn39D HG21C