Reference - Detail
| RRC ID | 12580 |
|---|---|
| Author | Sharifmoghadam MR, de Leon N, Hoya M, Curto MA, Valdivieso MH. |
| Title | Different steps of sexual development are differentially regulated by the Sec8p and Exo70p exocyst subunits. |
| Journal | FEMS Microbiol Lett |
| Abstract |
In this paper we show that in Schizosaccharomyces pombe, mating-specific cell adhesion is dependent on the exocyst subunit Sec8p, but independent of the exocyst subunit Exo70p. In the absence of Exo70p, the forespore membrane does not develop properly and the leading edge protein Meu14p is abnormally distributed. Additionally, the spindle pole body is aberrant in a significant number of exo70Delta asci. In both the sec8-1 and the exo70Delta mutants, the development of the spore cell wall is impaired. These results show that different steps of sexual development are differentially regulated by the exocyst and suggest the existence of exocyst subcomplexes with distinct roles in mating. |
| Volume | 305(1) |
| Pages | 71-80 |
| Published | 2010-4-1 |
| DOI | 10.1111/j.1574-6968.2010.01915.x |
| PII | FML1915 |
| PMID | 20180855 |
| MeSH | Carrier Proteins / physiology* Cell Adhesion* Cell Wall / metabolism Fungal Proteins / physiology* Gene Expression Regulation, Fungal* Intracellular Signaling Peptides and Proteins Protein Subunits / physiology Schizosaccharomyces / cytology Schizosaccharomyces / growth & development Schizosaccharomyces / physiology* Schizosaccharomyces pombe Proteins / physiology* Vesicular Transport Proteins / physiology* |
| IF | 1.987 |
| Times Cited | 5 |
| WOS Category | MICROBIOLOGY |
| Resource | |
| Yeast | |