論文 - 詳細
| RRC ID | 15418 |
|---|---|
| 著者 | Akiyama K, Maruyama M, Yamauchi S, Nakashima Y, Nakato T, Tago R, Sugahara T, Kishida T, Koba Y. |
| タイトル | Antimicrobiological activity of lignan: effect of benzylic oxygen and stereochemistry of 2,3-dibenzyl-4-butanolide and 3,4-dibenzyltetrahydrofuran lignans on activity. |
| ジャーナル | Biosci Biotechnol Biochem |
| Abstract |
The effect of oxidation degree at the benzylic position of 2,3-dibenzyl-4-butanolide and 3,4-dibenzyltetrahydrofuran lignans on the antimicrobiological activity was examined. The highest oxidation degree at the benzylic position of 2,3-dibenzyl-4-butanolide gave the greatest activity, and 3,4-dibenzoyltetrahydrofuran showed the highest antifungal activity. The relationship between stereochemistry and activity was also examined. Both enantiomers of cis-matairesinol were synthesized for the first time, one of the cis-matairesinols showing antibacterial activity. |
| 巻・号 | 71(7) |
| ページ | 1745-51 |
| 公開日 | 2007-7-1 |
| DOI | 10.1271/bbb.70168 |
| PII | JST.JSTAGE/bbb/70168 |
| PMID | 17617715 |
| MeSH | 4-Butyrolactone / chemistry 4-Butyrolactone / pharmacology Anti-Infective Agents / chemistry Anti-Infective Agents / pharmacology* Bacillus subtilis / drug effects Furans / chemistry Furans / pharmacology* Lignans / chemistry Lignans / pharmacology* Molecular Conformation Oxygen / chemistry* Pseudomonas fluorescens / drug effects Staphylococcus aureus / drug effects Structure-Activity Relationship |
| IF | 1.516 |
| 引用数 | 24 |
| WOS 分野 | FOOD SCIENCE & TECHNOLOGY CHEMISTRY, APPLIED BIOTECHNOLOGY & APPLIED MICROBIOLOGY BIOCHEMISTRY & MOLECULAR BIOLOGY |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | Patent(IFI CLAIMS) |
| 各媒体での言及数の合計 | 1 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| 一般微生物 | JCM 1649 JCM 6977 JCN 7579 JCM 11481 |