論文 - 詳細
| RRC ID | 15444 |
|---|---|
| 著者 | Tada S, Katakura Y, Ninomiya K, Shioya S. |
| タイトル | Fed-batch coculture of Lactobacillus kefiranofaciens with Saccharomyces cerevisiae for effective production of kefiran. |
| ジャーナル | J Biosci Bioeng |
| Abstract |
In a batch coculture of kefiran-producing lactic acid bacteria Lactobacillus kefiranofaciens and lactate-assimilating yeast Saccharomyces cerevisiae, lactate accumulation in the medium was observed, which inhibited kefiran production. To enhance kefiran productivity by preventing lactate accumulation, we conducted lactose-feeding batch operation with feedforward/feedback control during the coculture, so that the lactate production rate of L. kefiranofaciens was balanced with the lactate consumption rate of S. cerevisiae. The lactate concentration was maintained at less than 6 g l(-1) throughout the fed-batch coculture using a 5 l jar fermentor, although the concentration reached 33 g l(-1) in the batch coculture. Kefiran production was increased to 6.3 g in 102 h in the fed-batch coculture, whereas 4.5 g kefiran was produced in 97 h in the batch coculture. The kefiran yield on lactose basis was increased up to 0.033 g g(-1) in the fed-batch coculture, whereas that in the batch coculture was 0.027 g g(-1). |
| 巻・号 | 103(6) |
| ページ | 557-62 |
| 公開日 | 2007-6-1 |
| DOI | 10.1263/jbb.103.557 |
| PII | S1389-1723(07)70104-4 |
| PMID | 17630128 |
| MeSH | Biotechnology Coculture Techniques / methods* Feedback Fermentation Kinetics Lactic Acid / metabolism Lactobacillus / metabolism* Models, Biological Polysaccharides / biosynthesis* Saccharomyces cerevisiae / metabolism* |
| IF | 2.366 |
| 引用数 | 17 |
| WOS 分野 | FOOD SCIENCE & TECHNOLOGY BIOTECHNOLOGY & APPLIED MICROBIOLOGY |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | Patent(IFI CLAIMS) |
| 各媒体での言及数の合計 | 2 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| 一般微生物 | JCM 6985 |