論文 - 詳細
| RRC ID | 15493 |
|---|---|
| 著者 | Liedtke D, Erhard I, Schartl M. |
| タイトル | snail gene expression in the medaka, Oryzias latipes. |
| ジャーナル | Gene Expr Patterns |
| Abstract |
Snail transcription factors have prominent roles during embryonic development of vertebrates. They are often involved in cell migration processes during neural crest development, epithelial-mesenchymal transition and cancer progression. Comparative expression studies of snai gene family members in different vertebrate species are expected to contribute to a better understanding of their roles during development and reflect their evolutionary history. To investigate and to compare the expression patterns of snai genes in a second main fish model we used the medaka fish (Oryzias latipes), a complementary teleost model to zebrafish. We identified three snai gene family members, snai1a, snai1b and snai2. Phylogenetic and synteny analysis show a close relatedness of all family members to other vertebrate snai genes. Surprisingly, no homologue of snai3 could be identified in medaka, although this gene is present in zebrafish and the puffer fishes. Here we demonstrate that while most expression domains of medaka snai genes are comparable to zebrafish, the contribution of the individual paralogs to the overall pattern differs between the two teleosts and indicate lineage specific expression shuffling. |
| 巻・号 | 11(3-4) |
| ページ | 181-9 |
| 公開日 | 2011-1-1 |
| DOI | 10.1016/j.gep.2010.11.003 |
| PII | S1567-133X(10)00118-3 |
| PMID | 21094700 |
| MeSH | Animals Gastrula / metabolism Gastrulation / physiology Gene Expression Regulation, Developmental In Situ Hybridization Likelihood Functions Mesoderm / metabolism Neural Crest / cytology Neural Crest / metabolism Oryzias / embryology Oryzias / genetics* Phylogeny Sequence Alignment Snail Family Transcription Factors Somites / metabolism Transcription Factors / genetics Transcription Factors / metabolism* Transcription, Genetic Zebrafish / embryology Zebrafish / genetics |
| IF | 0.897 |
| 引用数 | 2 |
| WOS 分野 | DEVELOPMENTAL BIOLOGY GENETICS & HEREDITY |
| オルトメトリクス指標 |
オルトメトリクス指標項目
|
| 各媒体での言及数の合計 | 0 |
| リソース情報 | |
| メダカ | database carbio strain (OK-Cab (MT830)) i3 albino strain(i-3(b) (MT65)) |