RRC ID |
15612
|
著者 |
Tago R, Yamauchi S, Maruyama M, Akiyama K, Sugahara T, Kishida T, Koba Y.
|
タイトル |
Structure-antibacterial activity relationship for 9-O,9'-O-demethyl (+)-virgatusin.
|
ジャーナル |
Biosci Biotechnol Biochem
|
Abstract |
The relationship between the antibacterial activity and structure of 9-O,9'-O-demethyl (+)-virgatusin (Virg 3) was examined. The conversion of hydroxy groups on the 9 and 9' positions to amino groups increased the activity. It was found that the 3'-methoxy group was more important for higher activity than the 4'-methoxy group on the 7'-phenyl group, and that the 3,4-methylenedioxy group on the 7-phenyl group was necessary for activity.
|
巻・号 |
72(4)
|
ページ |
1032-7
|
公開日 |
2008-4-1
|
DOI |
10.1271/bbb.70783
|
PII |
JST.JSTAGE/bbb/70783
|
PMID |
18391445
|
MeSH |
Anti-Bacterial Agents / chemistry*
Anti-Bacterial Agents / pharmacology*
Biological Products / chemistry
Biological Products / pharmacology
Furans / chemistry*
Furans / pharmacology*
Lignans / chemistry
Lignans / pharmacology
Microbial Sensitivity Tests
Structure-Activity Relationship
|
IF |
1.516
|
引用数 |
6
|
WOS 分野
|
FOOD SCIENCE & TECHNOLOGY
CHEMISTRY, APPLIED
BIOTECHNOLOGY & APPLIED MICROBIOLOGY
BIOCHEMISTRY & MOLECULAR BIOLOGY
|
リソース情報 |
一般微生物 |
JCM 1649
JCM 6977
JCM 11481 |