RRC ID 15616
Author Nakato T, Tago R, Akiyama K, Maruyama M, Sugahara T, Kishida T, Yamauchi S.
Title Stereoselective construction of tetra-substituted tetrahydrofuran compounds from benzylic hemiacetal in the presence of H2 and a Pd catalyst: stereoselective synthesis of a stereoisomer of (-)-virgatusin and its antimicrobiological activity.
Journal Biosci Biotechnol Biochem
Abstract Tetra-substituted tetrahydrofuran compounds were stereoselectively prepared from benzylic hemiacetal in the neutral condition by employing the simple reagent, H(2), and a Pd catalyst. The stereoselective conversion of benzylic hemiacetal to two different stereoisomers of the tetrasubstituted tetrahydrofuran compound was observed. One of these tetrahydrofuran compounds was converted to the virgatusin stereoisomer to estimate its antimicrobiological activity.
Volume 72(1)
Pages 197-203
Published 2008-1-1
DOI 10.1271/bbb.70554
PII JST.JSTAGE/bbb/70554
PMID 18175922
MeSH Anti-Bacterial Agents / chemical synthesis* Anti-Bacterial Agents / chemistry Benzyl Compounds Catalysis Furans / chemical synthesis* Furans / chemistry Magnetic Resonance Spectroscopy Models, Molecular Optical Rotation Polymers / chemistry Solvents
IF 1.516
Times Cited 6
WOS Category FOOD SCIENCE & TECHNOLOGY CHEMISTRY, APPLIED BIOTECHNOLOGY & APPLIED MICROBIOLOGY BIOCHEMISTRY & MOLECULAR BIOLOGY
Resource
General Microbes JCM 11481