RRC ID |
15616
|
Author |
Nakato T, Tago R, Akiyama K, Maruyama M, Sugahara T, Kishida T, Yamauchi S.
|
Title |
Stereoselective construction of tetra-substituted tetrahydrofuran compounds from benzylic hemiacetal in the presence of H2 and a Pd catalyst: stereoselective synthesis of a stereoisomer of (-)-virgatusin and its antimicrobiological activity.
|
Journal |
Biosci Biotechnol Biochem
|
Abstract |
Tetra-substituted tetrahydrofuran compounds were stereoselectively prepared from benzylic hemiacetal in the neutral condition by employing the simple reagent, H(2), and a Pd catalyst. The stereoselective conversion of benzylic hemiacetal to two different stereoisomers of the tetrasubstituted tetrahydrofuran compound was observed. One of these tetrahydrofuran compounds was converted to the virgatusin stereoisomer to estimate its antimicrobiological activity.
|
Volume |
72(1)
|
Pages |
197-203
|
Published |
2008-1-1
|
DOI |
10.1271/bbb.70554
|
PII |
JST.JSTAGE/bbb/70554
|
PMID |
18175922
|
MeSH |
Anti-Bacterial Agents / chemical synthesis*
Anti-Bacterial Agents / chemistry
Benzyl Compounds
Catalysis
Furans / chemical synthesis*
Furans / chemistry
Magnetic Resonance Spectroscopy
Models, Molecular
Optical Rotation
Polymers / chemistry
Solvents
|
IF |
1.516
|
Times Cited |
6
|
WOS Category
|
FOOD SCIENCE & TECHNOLOGY
CHEMISTRY, APPLIED
BIOTECHNOLOGY & APPLIED MICROBIOLOGY
BIOCHEMISTRY & MOLECULAR BIOLOGY
|
Resource |
General Microbes |
JCM 11481 |