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  • Search Condition : Filter (MeSH = Models, Molecular)
Species Resource Title
Human and Animal Cells MC3T3-E1(RCB1126) Novel therapeutic agents for bone resorption. Part 1. Synthesis and protonation thermodynamics of poly(amido-amine)s containing bis-phosphonate residues.
Human and Animal Cells RERF-LC-AI(RCB0444) A unique hinge binder of extremely selective aminopyridine-based Mps1 (TTK) kinase inhibitors with cellular activity.
Human and Animal Cells Hep G2(RCB1886) Identification of a New Type of Covalent PPARγ Agonist using a Ligand-Linking Strategy.
Human and Animal Cells HuH-7 First Selective Small Molecule Inhibitor of FGFR4 for the Treatment of Hepatocellular Carcinomas with an Activated FGFR4 Signaling Pathway.
Human and Animal Cells LC-2/ad(RCB0440) Antitumor Activity and Acquired Resistance Mechanism of Dovitinib (TKI258) in RET-Rearranged Lung Adenocarcinoma.
Human and Animal Cells DT40(RCB1464) , PLC-γ2^(-) DT40(RCB1469) Rac-mediated Stimulation of Phospholipase Cγ2 Amplifies B Cell Receptor-induced Calcium Signaling.
Human and Animal Cells COS-7(RCB0539) Functional characterization of 12 allelic variants of CYP2C8 by assessment of paclitaxel 6α-hydroxylation and amodiaquine N-deethylation.
DNA material pUC18-HTK (with promoter) (RDB03436) Thermus thermophilus Argonaute Functions in the Completion of DNA Replication.
DNA material pMal-c2X MBP-GFP1-10 (RDB17883) Stabilization of microtubules by encapsulation of the GFP using a Tau-derived peptide.
Prokaryotes E. coli Non-pathogenic Escherichia coli acquires virulence by mutating a growth-essential LPS transporter.
Silkworms Non-pathogenic Escherichia coli acquires virulence by mutating a growth-essential LPS transporter.
Human and Animal Cells HeLa Haemorrhagic snake venom metalloproteases and human ADAMs cleave LRP5/6, which disrupts cell-cell adhesions in vitro and induces haemorrhage in vivo.
Human and Animal Cells Ba/F3 Characterization of EGFR T790M, L792F, and C797S Mutations as Mechanisms of Acquired Resistance to Afatinib in Lung Cancer.
Human and Animal Cells TGBC11TKB(RCB1148) Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma.
Human and Animal Cells HeLa Arginine-rich cell-penetrating peptide-modified extracellular vesicles for active macropinocytosis induction and efficient intracellular delivery.
Human and Animal Cells PC-9(RCB4455) Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Oncogenic EGFR Mutants with Selectivity over Wild-Type EGFR.
Human and Animal Cells PC-9(RCB4455) Discovery of 1-{(3R,4R)-3-[({5-Chloro-2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)methyl]-4-methoxypyrrolidin-1-yl}prop-2-en-1-one (PF-06459988), a Potent, WT Sparing, Irreversible Inhibitor of T790M-Containing EGFR Mutants.
Human and Animal Cells COS-7(RCB0539) Structure of IZUMO1-JUNO reveals sperm-oocyte recognition during mammalian fertilization.
Human and Animal Cells Ba/F3(RCB0805) , LC-2/ad(RCB0440) Alectinib shows potent antitumor activity against RET-rearranged non-small cell lung cancer.
Human and Animal Cells NBT-T2(RCB1370) Sangiangols A and B, Two New Dolabellanes from an Indonesian Marine Soft Coral, Anthelia sp.