Reference - Detail
| RRC ID | 15666 |
|---|---|
| Author | Golubev VI, Kulakovskaia TV, Shashkov AS, Kulakovskaia EV, Golubev NV. |
| Title | [Antifungal cellobiose lipid secreted by the epiphytic yeast Pseudozyma graminicola]. |
| Journal | Mikrobiologiia |
| Abstract |
The yeast Pseudozyma graminicola isolated from plants inhibited growth of almost all ascomycetes and basidiomycetes tested (over 270 species of ca. 100 genera) including pathogenic species. This yeast secreted a fungicidal agent, which was identified as a glycolipid composed of cellobiose residue with two O-substituents (acetyl and 3-hydroxycaproic acid) and 2,15,16-trihydroxypalmitic acid. The release of ATP from the glycolipid-treated cells indicated that this glycolipid impaired the permeability of the cytoplasmic membrane. Basidiomycetes were more sensitive to the cellobiose lipid than ascomycetes. |
| Volume | 77(2) |
| Pages | 201-6 |
| Published | 2008-1-1 |
| PMID | 18522321 |
| MeSH | Antifungal Agents / chemistry Antifungal Agents / metabolism* Antifungal Agents / pharmacology* Ascomycota / drug effects* Ascomycota / growth & development Ascomycota / metabolism Basidiomycota / drug effects* Basidiomycota / growth & development Basidiomycota / metabolism Cell Membrane / metabolism Edible Grain / microbiology Glycolipids / chemistry Glycolipids / metabolism* Glycolipids / pharmacology* Permeability / drug effects Yeasts / isolation & purification Yeasts / metabolism* |
| Resource | |
| General Microbes | JCM 1542 |