論文 - 詳細
| RRC ID | 15805 |
|---|---|
| 著者 | Yoneyama F, Ohno K, Imura Y, Li M, Zendo T, Nakayama J, Matsuzaki K, Sonomoto K. |
| タイトル | Lacticin Q-mediated selective toxicity depending on physicochemical features of membrane components. |
| ジャーナル | Antimicrob Agents Chemother |
| Abstract |
Lacticin Q, a lactococcal pore-forming bacteriocin, shows activity toward Gram-positive bacteria but not Gram-negative bacteria. Lacticin Q did not induce permeability of the outer membrane of Gram-negative bacteria. Experiments using model membranes containing outer membrane components suggested that lacticin Q binds to the outer membrane of Gram-negative bacteria but is unable to penetrate it. The lack of activity of lacticin Q was attributed to physicochemical features of the outer membrane components. |
| 巻・号 | 55(5) |
| ページ | 2446-50 |
| 公開日 | 2011-5-1 |
| DOI | 10.1128/AAC.00808-10 |
| PII | AAC.00808-10 |
| PMID | 21282423 |
| PMC | PMC3088220 |
| MeSH | Bacteriocins / pharmacology* Cell Membrane / drug effects* Cell Membrane / metabolism* Gram-Negative Bacteria / drug effects Gram-Negative Bacteria / metabolism Gram-Positive Bacteria / drug effects Gram-Positive Bacteria / metabolism Microbial Sensitivity Tests Models, Biological |
| IF | 4.904 |
| 引用数 | 16 |
| WOS 分野 | PHARMACOLOGY & PHARMACY MICROBIOLOGY |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 各媒体での言及数の合計 | 0 |
| リソース情報 | |
| 一般微生物 | JCM 2257 JCM 5890 |