RRC ID 15960
著者 McTaggart LR, Lei E, Richardson SE, Hoang L, Fothergill A, Zhang SX.
タイトル Rapid identification of Cryptococcus neoformans and Cryptococcus gattii by matrix-assisted laser desorption ionization-time of flight mass spectrometry.
ジャーナル J Clin Microbiol
Abstract Compared to DNA sequence analysis, matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) correctly identified 100% of Cryptococcus species, distinguishing the notable pathogens Cryptococcus neoformans and C. gattii. Identification was greatly enhanced by supplementing a commercial spectral library with additional entries to account for subspecies variability.
巻・号 49(8)
ページ 3050-3
公開日 2011-8-1
DOI 10.1128/JCM.00651-11
PII JCM.00651-11
PMID 21653762
PMC PMC3147715
MeSH Cryptococcus gattii / chemistry* Cryptococcus gattii / classification* Cryptococcus neoformans / chemistry* Cryptococcus neoformans / classification* DNA, Fungal / chemistry DNA, Fungal / genetics Humans Microbiological Techniques / methods* Mycology / methods* Sensitivity and Specificity Sequence Analysis, DNA / methods Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods*
IF 5.897
引用数 64
WOS 分野 MICROBIOLOGY
リソース情報
一般微生物 JCM 2466 JCM 3685 JCM 6359 JCM 7255 JCM 8115 JCM 9195