論文 - 詳細
| RRC ID | 17456 |
|---|---|
| 著者 | Furuhata K, Ogihara K, Ishizaki N, Oonaka K, Yoshida Y, Goto K, Hara M, Miyamoto H, Yoshida S, Fukuyama M. |
| タイトル | Identification of Legionella londiniensis isolated from hot spring water samples in Shizuoka, Japan, and cytotoxicity of isolates. |
| ジャーナル | J Infect Chemother |
| Abstract |
As part of an epidemiological study on legionellosis, we attempted to isolate Legionella spp. from hot spring water and were able to isolate L. londiniensis HYKF-90505 (=JCM 16338), confirming that L. londiniensis inhabits hot spring water in Japan. To investigate the disease potential of L. londiniensis, we examined its ability to grow intracellularly within Acanthamoeba sp. JAC/E1 strain. The isolated HYKF-90505 was able to grow within Acanthamoeba sp. JAC/E1 strain, and we confirmed also that the HYKF-90505 strain showed cytotoxicity for cultured cells such as J774.1 (JCRB0018). However, in a culture of human U937 cells, the bacterial count was not increased by the intracellular growth of the HYKF-90505 strain. Cells infected for 24 h and stained using the Giménez method showed no intracellular growth of the HYKF-90505 strain. Thus, the isolate appears to be weakly pathogenic to humans. |
| 巻・号 | 16(5) |
| ページ | 367-71 |
| 公開日 | 2010-10-1 |
| DOI | 10.1007/s10156-010-0062-8 |
| PII | S1341-321X(10)70585-7 |
| PMID | 20419328 |
| MeSH | Acanthamoeba / microbiology Hot Springs / microbiology* Humans Intracellular Space / microbiology Japan Legionella / isolation & purification* Legionella / pathogenicity U937 Cells Water Microbiology |
| IF | 1.722 |
| 引用数 | 8 |
| WOS 分野 | PHARMACOLOGY & PHARMACY INFECTIOUS DISEASES |
| オルトメトリクス指標 |
オルトメトリクス指標項目
|
| 最多言及媒体 | Wikipedia |
| 各媒体での言及数の合計 | 1 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| 一般微生物 | JCM 16338 |