RRC ID 18189
Author Kawamoto S, Kaneoke M, Ohkouchi K, Amano Y, Takaoka Y, Kume K, Aki T, Yamashita S, Watanabe K, Kadowaki M, Hirata D, Ono K.
Title Sake lees fermented with lactic acid bacteria prevents allergic rhinitis-like symptoms and IgE-mediated basophil degranulation.
Journal Biosci Biotechnol Biochem
Abstract We tested the effect of oral administration of fermented sake lees with lactic acid bacteria (FESLAB) on a murine model of allergic rhinitis upon immunization and nasal sensitization with ovalbumin (OVA). We used Lactobacillus paracasei NPSRIk-4 (isolated from sake lees), and L. brevis NPSRIv-8 (from fermented milk) as starter strains to produce the FESLAB. Oral FESLAB administration resulted in the development of significantly fewer sneezing symptoms than those seen in sham control animals given sterile water. We also found that FESLAB suppressed the allergen-induced degranulation of RBL2H3 rat basophilic leukemia cells.
Volume 75(1)
Pages 140-4
Published 2011-1-1
DOI 10.1271/bbb.100541
PII JST.JSTAGE/bbb/100541
PMID 21228477
MeSH Animals Basophils / cytology* Basophils / immunology Cell Degranulation* Cell Line, Tumor Dietary Supplements Female Fermentation* Hypersensitivity / complications Immunoglobulin E / immunology* Lactobacillus / metabolism* Mice Rats Rhinitis / complications Rhinitis / immunology Rhinitis / prevention & control* Wine*
IF 1.516
Times Cited 17
WOS Category FOOD SCIENCE & TECHNOLOGY BIOTECHNOLOGY & APPLIED MICROBIOLOGY CHEMISTRY, APPLIED BIOCHEMISTRY & MOLECULAR BIOLOGY
Resource
Human and Animal Cells RBL 2H3(RCB2782)