Reference - Detail
RRC ID | 18189 |
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Author | Kawamoto S, Kaneoke M, Ohkouchi K, Amano Y, Takaoka Y, Kume K, Aki T, Yamashita S, Watanabe K, Kadowaki M, Hirata D, Ono K. |
Title | Sake lees fermented with lactic acid bacteria prevents allergic rhinitis-like symptoms and IgE-mediated basophil degranulation. |
Journal | Biosci Biotechnol Biochem |
Abstract |
We tested the effect of oral administration of fermented sake lees with lactic acid bacteria (FESLAB) on a murine model of allergic rhinitis upon immunization and nasal sensitization with ovalbumin (OVA). We used Lactobacillus paracasei NPSRIk-4 (isolated from sake lees), and L. brevis NPSRIv-8 (from fermented milk) as starter strains to produce the FESLAB. Oral FESLAB administration resulted in the development of significantly fewer sneezing symptoms than those seen in sham control animals given sterile water. We also found that FESLAB suppressed the allergen-induced degranulation of RBL2H3 rat basophilic leukemia cells. |
Volume | 75(1) |
Pages | 140-4 |
Published | 2011-1-1 |
DOI | 10.1271/bbb.100541 |
PII | JST.JSTAGE/bbb/100541 |
PMID | 21228477 |
MeSH | Animals Basophils / cytology* Basophils / immunology Cell Degranulation* Cell Line, Tumor Dietary Supplements Female Fermentation* Hypersensitivity / complications Immunoglobulin E / immunology* Lactobacillus / metabolism* Mice Rats Rhinitis / complications Rhinitis / immunology Rhinitis / prevention & control* Wine* |
IF | 1.516 |
Times Cited | 17 |
WOS Category | FOOD SCIENCE & TECHNOLOGY BIOTECHNOLOGY & APPLIED MICROBIOLOGY CHEMISTRY, APPLIED BIOCHEMISTRY & MOLECULAR BIOLOGY |
Resource | |
Human and Animal Cells | RBL 2H3(RCB2782) |