Reference - Detail
| RRC ID | 18589 |
|---|---|
| Author | Tagaya M, Yamazaki T, Tsuya D, Sugimoto Y, Hanagata N, Ikoma T. |
| Title | Nano/microstructural effect of hydroxyapatite nanocrystals on hepatocyte cell aggregation and adhesion. |
| Journal | Macromol Biosci |
| Abstract |
Hepatocyte cell aggregation and adhesion to HAp nanocrystals covered with SU-8 polymer micropatterns by nano/microfabrication techniques is demonstrated. The surface roughness and wettability of the HAp nanocrystals are significantly different from those of the SU-8 polymer. QCM-D and microscopic observation clearly reveal that the cells realize the surface properties to form aggregation and preferentially adhere to the HAp nanocrystals at 2 h after seeding, indicating the importance of the microstructures as well as the interfacial phenomena at a nanometer scale. |
| Volume | 11(11) |
| Pages | 1586-93 |
| Published | 2011-11-10 |
| DOI | 10.1002/mabi.201100182 |
| PMID | 22052565 |
| MeSH | Biocompatible Materials / chemical synthesis* Biocompatible Materials / metabolism Biocompatible Materials / pharmacology Cell Adhesion Cell Aggregation Crystallography, X-Ray Durapatite / chemistry Durapatite / metabolism* Durapatite / pharmacology Epoxy Compounds / chemistry Hepatocytes / drug effects Hepatocytes / physiology* Humans Microscopy, Atomic Force Nanoparticles / chemistry Nanoparticles / ultrastructure Particle Size Photochemical Processes Surface Properties Tissue Engineering / methods* Tumor Cells, Cultured |
| IF | 3.416 |
| Times Cited | 13 |
| WOS Category | POLYMER SCIENCE BIOCHEMISTRY & MOLECULAR BIOLOGY MATERIALS SCIENCE, BIOMATERIALS |
| Altmetric score |
オルトメトリクス指標項目
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| The most frequently cited source | Patent(IFI CLAIMS) |
| Total number of mentions | 1 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| Human and Animal Cells | Hep G2 (RCB1648) |