Reference - Detail
| RRC ID | 1871 |
|---|---|
| Author | Norholm MH, Nour-Eldin HH, Brodersen P, Mundy J, Halkier BA. |
| Title | Expression of the Arabidopsis high-affinity hexose transporter STP13 correlates with programmed cell death. |
| Journal | FEBS Lett |
| Abstract |
We report the biochemical characterization in Xenopus oocytes of the Arabidopsis thaliana membrane protein, STP13, as a high affinity, hexose-specific H(+)-symporter. Studies with kinase activators suggest that it is negatively regulated by phosphorylation. STP13 promoter GFP reporter lines show GFP expression only in the vascular tissue in emerging petals under non-stressed conditions. Quantitative PCR and the pSTP13-GFP plants show induction of STP13 in programmed cell death (PCD) obtained by treatments with the fungal toxin fumonisin B1 and the pathogen Pseudomonas syringae. A role for STP13 in PCD is supported by microarray data from e.g. plants undergoing senescence and a strong correlation between STP13 transcripts and the PCD phenotype in different accelerated cell death (acd11) mutants. |
| Volume | 580(9) |
| Pages | 2381-7 |
| Published | 2006-4-17 |
| DOI | 10.1016/j.febslet.2006.03.064 |
| PII | S0014-5793(06)00380-2 |
| PMID | 16616142 |
| MeSH | Animals Apoptosis / drug effects Apoptosis / genetics* Apoptosis Regulatory Proteins / genetics Apoptosis Regulatory Proteins / metabolism Arabidopsis Arabidopsis Proteins / biosynthesis* Arabidopsis Proteins / genetics Arabidopsis Proteins / metabolism Cells, Cultured Cellular Senescence / drug effects Cellular Senescence / genetics Enzyme Inhibitors / pharmacology Fumonisins / pharmacology Gene Expression* Membrane Transport Proteins / genetics Membrane Transport Proteins / metabolism Monosaccharide Transport Proteins / biosynthesis* Monosaccharide Transport Proteins / genetics Monosaccharide Transport Proteins / metabolism Oocytes Symporters / biosynthesis* Symporters / genetics Xenopus |
| IF | 3.057 |
| Times Cited | 66 |
| WOS Category | BIOPHYSICS BIOCHEMISTRY & MOLECULAR BIOLOGY CELL BIOLOGY |
| Resource | |
| Arabidopsis / Cultured plant cells, genes | pda03530 |