RRC ID 19083
著者 Sawa N, Wilaipun P, Kinoshita S, Zendo T, Leelawatcharamas V, Nakayama J, Sonomoto K.
タイトル Isolation and characterization of enterocin W, a novel two-peptide lantibiotic produced by Enterococcus faecalis NKR-4-1.
ジャーナル Appl Environ Microbiol
Abstract Enterococcus faecalis NKR-4-1 isolated from pla-ra produces a novel two-peptide lantibiotic, termed enterocin W, comprising Wα and Wβ. The structure of enterocin W exhibited similarity with that of plantaricin W. The two peptides acted synergistically, and their order of binding to the cell membrane was important for their inhibitory activity.
巻・号 78(3)
ページ 900-3
公開日 2012-2-1
DOI 10.1128/AEM.06497-11
PII AEM.06497-11
PMID 22138996
PMC PMC3264125
MeSH Amino Acid Sequence Anti-Bacterial Agents / pharmacology Bacteriocins / chemistry Bacteriocins / isolation & purification* Bacteriocins / metabolism* Bacteriocins / pharmacology Base Sequence Bridged-Ring Compounds / chemistry Bridged-Ring Compounds / isolation & purification Bridged-Ring Compounds / metabolism Bridged-Ring Compounds / pharmacology Cell Membrane / metabolism DNA, Bacterial / chemistry DNA, Bacterial / genetics Dipeptides / chemistry Dipeptides / isolation & purification Dipeptides / metabolism Dipeptides / pharmacology Drug Synergism Enterococcus faecalis / metabolism* Genes, Bacterial / genetics Molecular Sequence Data Sequence Analysis, DNA
IF 4.016
引用数 27
WOS 分野 BIOTECHNOLOGY & APPLIED MICROBIOLOGY MICROBIOLOGY
リソース情報
一般微生物 JCM 1157 JCM 1465 JCM 2257 JCM 2504 JCM 5803 JCM 5885 JCM 7638