RRC ID 19094
著者 Mimitsuka T, Na K, Morita K, Sawai H, Minegishi S, Henmi M, Yamada K, Shimizu S, Yonehara T.
タイトル A membrane-integrated fermentation reactor system: its effects in reducing the amount of sub-raw materials for D-lactic acid continuous fermentation by Sporolactobacillus laevolacticus.
ジャーナル Biosci Biotechnol Biochem
Abstract Continuous fermentation by retaining cells with a membrane-integrated fermentation reactor (MFR) system was found to reduce the amount of supplied sub-raw material. If the amount of sub-raw material can be reduced, continuous fermentation with the MFR system should become a more attractive process for industrialization, due to decreased material costs and loads during the refinement process. Our findings indicate that the production rate decreased when the amount of the sub-raw material was reduced in batch fermentation, but did not decrease during continuous fermentation with Sporolactobacillus laevolacticus. Moreover, continuous fermentation with a reduced amount of sub-raw material resulted in a productivity of 11.2 g/L/h over 800 h. In addition, the index of industrial process applicability used in the MFR system increased by 6.3-fold as compared with the conventional membrane-based fermentation reactor previously reported, suggesting a potential for the industrialization of this D-lactic acid continuous fermentation process.
巻・号 76(1)
ページ 67-72
公開日 2012-1-1
DOI 10.1271/bbb.110499
PII JST.JSTAGE/bbb/110499
PMID 22277286
MeSH Bacillales / metabolism* Bioreactors / microbiology* Fermentation* Lactic Acid / biosynthesis* Membranes, Artificial* Time Factors Yeasts / chemistry
IF 1.516
引用数 8
WOS 分野 FOOD SCIENCE & TECHNOLOGY BIOTECHNOLOGY & APPLIED MICROBIOLOGY CHEMISTRY, APPLIED BIOCHEMISTRY & MOLECULAR BIOLOGY
リソース情報
一般微生物 JCM 2513