RRC ID |
19094
|
著者 |
Mimitsuka T, Na K, Morita K, Sawai H, Minegishi S, Henmi M, Yamada K, Shimizu S, Yonehara T.
|
タイトル |
A membrane-integrated fermentation reactor system: its effects in reducing the amount of sub-raw materials for D-lactic acid continuous fermentation by Sporolactobacillus laevolacticus.
|
ジャーナル |
Biosci Biotechnol Biochem
|
Abstract |
Continuous fermentation by retaining cells with a membrane-integrated fermentation reactor (MFR) system was found to reduce the amount of supplied sub-raw material. If the amount of sub-raw material can be reduced, continuous fermentation with the MFR system should become a more attractive process for industrialization, due to decreased material costs and loads during the refinement process. Our findings indicate that the production rate decreased when the amount of the sub-raw material was reduced in batch fermentation, but did not decrease during continuous fermentation with Sporolactobacillus laevolacticus. Moreover, continuous fermentation with a reduced amount of sub-raw material resulted in a productivity of 11.2 g/L/h over 800 h. In addition, the index of industrial process applicability used in the MFR system increased by 6.3-fold as compared with the conventional membrane-based fermentation reactor previously reported, suggesting a potential for the industrialization of this D-lactic acid continuous fermentation process.
|
巻・号 |
76(1)
|
ページ |
67-72
|
公開日 |
2012-1-1
|
DOI |
10.1271/bbb.110499
|
PII |
JST.JSTAGE/bbb/110499
|
PMID |
22277286
|
MeSH |
Bacillales / metabolism*
Bioreactors / microbiology*
Fermentation*
Lactic Acid / biosynthesis*
Membranes, Artificial*
Time Factors
Yeasts / chemistry
|
IF |
1.516
|
引用数 |
8
|
WOS 分野
|
FOOD SCIENCE & TECHNOLOGY
BIOTECHNOLOGY & APPLIED MICROBIOLOGY
CHEMISTRY, APPLIED
BIOCHEMISTRY & MOLECULAR BIOLOGY
|
リソース情報 |
一般微生物 |
JCM 2513 |