RRC ID |
19175
|
著者 |
Fujita S, Ninomiya M, Efdi M, Ohguchi K, Nozawa Y, Koketsu M.
|
タイトル |
Isolation of chemical constituents from Enicosanthum cupulare (King) Airy-Shaw.
|
ジャーナル |
Nat Prod Res
|
Abstract |
Six chemical constituents were isolated from Enicosanthum cupulare (King) Airy-Shaw. The structures of the isolated compounds were determined using 1D, 2D-NMR and were found to be identical to those previously reported for these compounds. Three aporphine alkaloids, O-methylmoschatoline, liriodenine and oxostephanine were isolated from this plant for the first time. In addition, we examined the effects of these compounds on melanogenesis in murine B16 melanoma cells; O-methylmoschatoline increased melanin content in these cells.
|
巻・号 |
24(17)
|
ページ |
1630-6
|
公開日 |
2010-10-1
|
DOI |
10.1080/14786411003774338
|
PII |
928180345
|
PMID |
20954090
|
MeSH |
Animals
Annonaceae / chemistry*
Chromatography, Gel
Magnetic Resonance Spectroscopy
Melanoma, Experimental / metabolism
Melanoma, Experimental / pathology
Mice
Plant Extracts / pharmacology*
Spectrometry, Mass, Fast Atom Bombardment
|
IF |
2.158
|
引用数 |
6
|
WOS 分野
|
CHEMISTRY, APPLIED
CHEMISTRY, MEDICINAL
|
リソース情報 |
ヒト・動物細胞 |
B16 melanoma 4A5(RCB0557) |