| RRC ID |
2076
|
| 著者 |
Komatsuda T, Pourkheirandish M, He C, Azhaguvel P, Kanamori H, Perovic D, Stein N, Graner A, Wicker T, Tagiri A, Lundqvist U, Fujimura T, Matsuoka M, Matsumoto T, Yano M.
|
| タイトル |
Six-rowed barley originated from a mutation in a homeodomain-leucine zipper I-class homeobox gene.
|
| ジャーナル |
Proc Natl Acad Sci U S A
|
| Abstract |
Increased seed production has been a common goal during the domestication of cereal crops, and early cultivators of barley (Hordeum vulgare ssp. vulgare) selected a phenotype with a six-rowed spike that stably produced three times the usual grain number. This improved yield established barley as a founder crop for the Near Eastern Neolithic civilization. The barley spike has one central and two lateral spikelets at each rachis node. The wild-type progenitor (H. vulgare ssp. spontaneum) has a two-rowed phenotype, with additional, strictly rudimentary, lateral rows; this natural adaptation is advantageous for seed dispersal after shattering. Until recently, the origin of the six-rowed phenotype remained unknown. In the present study, we isolated vrs1 (six-rowed spike 1), the gene responsible for the six-rowed spike in barley, by means of positional cloning. The wild-type Vrs1 allele (for two-rowed barley) encodes a transcription factor that includes a homeodomain with a closely linked leucine zipper motif. Expression of Vrs1 was strictly localized in the lateral-spikelet primordia of immature spikes, suggesting that the VRS1 protein suppresses development of the lateral rows. Loss of function of Vrs1 resulted in complete conversion of the rudimentary lateral spikelets in two-rowed barley into fully developed fertile spikelets in the six-rowed phenotype. Phylogenetic analysis demonstrated that the six-rowed phenotype originated repeatedly, at different times and in different regions, through independent mutations of Vrs1.
|
| 巻・号 |
104(4)
|
| ページ |
1424-9
|
| 公開日 |
2007-1-23
|
| DOI |
10.1073/pnas.0608580104
|
| PII |
0608580104
|
| PMID |
17220272
|
| PMC |
PMC1783110
|
| MeSH |
Base Sequence
Biological Evolution
Cloning, Molecular
DNA Primers
Genes, Homeobox*
Genes, Plant*
Hordeum / genetics*
Leucine Zippers*
Molecular Sequence Data
Mutation*
|
| IF |
9.412
|
| 引用数 |
320
|
|
WOS 分野
|
GENETICS & HEREDITY
|
| リソース情報 |
| オオムギ |
E527
I335
J247
U049
T637
E832
U013
C059
B327
U316
U607
K735 |
