• 520 Hits
  • Search Condition : Filter (MeSH = Mutation*)
Species Resource Title
Zebrafish hspGFFDMC130A , hspGFF62A A Forward Genetic Screen in Zebrafish Identifies the G-Protein-Coupled Receptor CaSR as a Modulator of Sensorimotor Decision Making.
Zebrafish SAGFF(LF)73A Integrin β1 activity is required for cardiovascular formation in zebrafish.
DNA material pMAMtracker-Luc (RDB19895) , pMAMtracker-Green (RDB19896) Novel reporters of mitochondria-associated membranes (MAM), MAMtrackers, demonstrate MAM disruption as a common pathological feature in amyotrophic lateral sclerosis.
Yeast BYP9683 (pST2303) , BYP9682 (pST2302) An efficient method for the isolation of interaction-null/impaired mutants using the yeast two-hybrid technique.
Human and Animal Cells COS-1(RCB0143) A novel and de novo splice-donor site mutation in intron 3 of the GH-1 gene in a patient with isolated growth hormone deficiency.
Human and Animal Cells MIA Paca2(RCB2094) , LU65(RCB1967) Characterisation of a novel KRAS G12C inhibitor ASP2453 that shows potent anti-tumour activity in KRAS G12C-mutated preclinical models.
General Microbes JCM12802 Improving the Substrate Affinity and Catalytic Efficiency of β-Glucosidase Bgl3A from Talaromyces leycettanus JCM12802 by Rational Design.
Zebrafish Tg(CM-isl1:GFP)rw0 INPP5K and SIL1 associated pathologies with overlapping clinical phenotypes converge through dysregulation of PHGDH.
DNA material pcDNA5-FRT-TO-EGFP-Mo DP1 (RDB19223) , pcDNA5-FRT-TO-EGFP-Mo Climp63 (RDB19222) Proteomics-Based Approach Identifies Altered ER Domain Properties by ALS-Linked VAPB Mutation.
Silkworms a47 , o45 , p50 Non-molting dwarf (nm-d) as a mutant of Bombyx mori with a defect in purine synthesis.
Human and Animal Cells LU99(RCB1900) , LU65(RCB1967) , IA-LM(RCB0554) The KRASG12C Inhibitor MRTX849 Provides Insight toward Therapeutic Susceptibility of KRAS-Mutant Cancers in Mouse Models and Patients.
Human and Animal Cells PC-9(RCB4455) A highly specific and sensitive massive parallel sequencer-based test for somatic mutations in non-small cell lung cancer.
Human and Animal Cells PC-9(RCB4455) Gefitinib induces premature senescence in non-small cell lung cancer cells with or without EGFR gene mutation.
Human and Animal Cells Ba/F3 Two novel ALK mutations mediate acquired resistance to the next-generation ALK inhibitor alectinib.
Human and Animal Cells PC-9(RCB4455) Trametinib overcomes KRAS-G12V-induced osimertinib resistance in a leptomeningeal carcinomatosis model of EGFR-mutant lung cancer.
Human and Animal Cells 293T(RCB2202) , KG-1(RCB1166) , K562 , F-36P(RCB0775) Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms.
Human and Animal Cells SK-N-SH(RCB0426) An in vitro model for Lewy body-like hyaline inclusion/astrocytic hyaline inclusion: induction by ER stress with an ALS-linked SOD1 mutation.
Yeast FY11064(MY3141) , FY10067(MY2167) Expression of the cancer-associated DNA polymerase ε P286R in fission yeast leads to translesion synthesis polymerase dependent hypermutation and defective DNA replication.
Barley seed samples of OUU305, OUU326 A novel mutant allele at the Cleistogamy 1 locus in barley.
Human and Animal Cells HuCCT1(RCB1960) Massive parallel sequencing uncovers actionable FGFR2-PPHLN1 fusion and ARAF mutations in intrahepatic cholangiocarcinoma.