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  • Search Condition : Filter (MeSH = Mutation*)
Species Resource Title
Human and Animal Cells LU99(RCB1900) , LU65(RCB1967) , IA-LM(RCB0554) The KRASG12C Inhibitor MRTX849 Provides Insight toward Therapeutic Susceptibility of KRAS-Mutant Cancers in Mouse Models and Patients.
Human and Animal Cells PC-9(RCB4455) A highly specific and sensitive massive parallel sequencer-based test for somatic mutations in non-small cell lung cancer.
Human and Animal Cells PC-9(RCB4455) Gefitinib induces premature senescence in non-small cell lung cancer cells with or without EGFR gene mutation.
Human and Animal Cells Ba/F3 Two novel ALK mutations mediate acquired resistance to the next-generation ALK inhibitor alectinib.
Human and Animal Cells PC-9(RCB4455) Trametinib overcomes KRAS-G12V-induced osimertinib resistance in a leptomeningeal carcinomatosis model of EGFR-mutant lung cancer.
Human and Animal Cells 293T(RCB2202) , KG-1(RCB1166) , K562 , F-36P(RCB0775) Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms.
Human and Animal Cells SK-N-SH(RCB0426) An in vitro model for Lewy body-like hyaline inclusion/astrocytic hyaline inclusion: induction by ER stress with an ALS-linked SOD1 mutation.
Human and Animal Cells Ba/F3(RCB0805) , WEHI-3(RCB0035) EGFR Exon 18 Mutations in Lung Cancer: Molecular Predictors of Augmented Sensitivity to Afatinib or Neratinib as Compared with First- or Third-Generation TKIs.
Human and Animal Cells 3T3 Swiss Albino(RCB1642) , A431(RCB0202) Binding of single-mutant epidermal growth factor (EGF) ligands alters the stability of the EGF receptor dimer and promotes growth signaling.
Human and Animal Cells RERF-LC-AI(RCB0444) , RERF-LC-KJ(RCB1313) RASA1 and NF1 are Preferentially Co-Mutated and Define A Distinct Genetic Subset of Smoking-Associated Non-Small Cell Lung Carcinomas Sensitive to MEK Inhibition.
Human and Animal Cells Ba/F3 Sequential ALK Inhibitors Can Select for Lorlatinib-Resistant Compound ALK Mutations in ALK-Positive Lung Cancer.
Human and Animal Cells KGN(RCB1154) An alternative miRISC targets a cancer-associated coding sequence mutation in FOXL2.
Human and Animal Cells PC-9(RCB4455) ONO-7475, a Novel AXL Inhibitor, Suppresses the Adaptive Resistance to Initial EGFR-TKI Treatment in EGFR-Mutated Non-Small Cell Lung Cancer.
Zebrafish Tg(TRPC24.5k :gap-Venus)rw037Tg , Tg(OMP2k :gap-CFP)rw034 Neuron-Derived Neurotrophic Factor Is Mutated in Congenital Hypogonadotropic Hypogonadism.
Human and Animal Cells MIA Paca2(RCB2094) An improved digital polymerase chain reaction protocol to capture low-copy KRAS mutations in plasma cell-free DNA by resolving 'subsampling' issues.
Human and Animal Cells Ba/F3 Characterization of EGFR T790M, L792F, and C797S Mutations as Mechanisms of Acquired Resistance to Afatinib in Lung Cancer.
Human and Animal Cells OP9(RCB1124) Level of RUNX1 activity is critical for leukemic predisposition but not for thrombocytopenia.
Human and Animal Cells JHOC-5(RCB1520) A functional proteogenomic analysis of endometrioid and clear cell carcinomas using reverse phase protein array and mutation analysis: protein expression is histotype-specific and loss of ARID1A/BAF250a is associated with AKT phosphorylation.
Human and Animal Cells PK-1(RCB1972) , PK-8(RCB2700) , PK-45P(RCB2141) , PK-59(RCB1901) , KP4(RCB1005) , NOR-P1(RCB2139) , T3M-4(RCB1021) Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer.
Human and Animal Cells MC3T3-E1(RCB1126) , GE1(RCB1709) Mutation of Spry2 induces proliferation and differentiation of osteoblasts but inhibits proliferation of gingival epithelial cells.