RRC ID 21187
著者 Hibayashi R, Imamura N.
タイトル Action mechanism of a selective anti-cyanobacterial compound, argimicin A.
ジャーナル J Antibiot (Tokyo)
Abstract Argimicin A is a potent anti-cyanobacterial compound produced by one of algae-lysing bacteria, Sphingomonas sp. M-17. Since the compound seemed to exhibit selective activities against cyanobacteria and such selectivity were considered to be quite rare, the mode of action of argimicin A was investigated. Argimicin A showed a unique delayed action, i.e., the cyanobacterial cell division continued until at least 36 hours treatment even though the decrement of oxygen evolution has been observed at 24 hours treatment. The compound is concluded to be a photosynthetic inhibitor which interrupts electron transport chain prior to photosystem II. From the preliminary fluorescent spectrum of argimicin A treated cyanobacterial cells, the site of action was speculated to be photo energy transfer from a cyanobacterial specific complex of accessory protein pigments, phycobilisome, to photosystem II.
巻・号 56(2)
ページ 154-9
公開日 2003-2-1
DOI 10.7164/antibiotics.56.154
PMID 12715875
MeSH Animals Anti-Bacterial Agents / pharmacology* Cyanobacteria / drug effects* Cyanobacteria / growth & development Cyanobacteria / metabolism Electron Transport Kinetics Light-Harvesting Protein Complexes Microscopy, Fluorescence Oxygen / metabolism Peptides* Photosynthetic Reaction Center Complex Proteins / metabolism Photosystem II Protein Complex Phycobilisomes Proteins / metabolism
IF 2.668
引用数 4
WOS 分野 BIOTECHNOLOGY & APPLIED MICROBIOLOGY PHARMACOLOGY & PHARMACY IMMUNOLOGY MICROBIOLOGY
リソース情報
藻類 NIES-81 NIES-41 NIES-45 NIES-230 NIES-592 NIES-204 NIES-102 NIES-298