論文 - 詳細
| RRC ID | 21543 |
|---|---|
| 著者 | Shimada A, Kawanishi T, Kaneko T, Yoshihara H, Yano T, Inohaya K, Kinoshita M, Kamei Y, Tamura K, Takeda H. |
| タイトル | Trunk exoskeleton in teleosts is mesodermal in origin. |
| ジャーナル | Nat Commun |
| Abstract |
The vertebrate mineralized skeleton is known to have first emerged as an exoskeleton that extensively covered the fossil jawless fish. The evolutionary origin of this exoskeleton has long been attributed to the emergence of the neural crest, but experimental evaluation for this is still poor. Here we determine the embryonic origin of scales and fin rays of medaka (teleost trunk exoskeletons) by applying long-term cell labelling methods, and demonstrate that both tissues are mesodermal in origin. Neural crest cells, however, fail to contribute to these tissues. This result suggests that the trunk neural crest has no skeletogenic capability in fish, instead highlighting the dominant role of the mesoderm in the evolution of the trunk skeleton. This further implies that the role of the neural crest in skeletogenesis has been predominant in the cephalic region from the early stage of vertebrate evolution. |
| 巻・号 | 4 |
| ページ | 1639 |
| 公開日 | 2013-1-1 |
| DOI | 10.1038/ncomms2643 |
| PII | ncomms2643 |
| PMID | 23535660 |
| PMC | PMC3615485 |
| MeSH | Animals Mesoderm / anatomy & histology* Oryzias / anatomy & histology* Skeleton* |
| IF | 12.121 |
| 引用数 | 51 |
| WOS 分野 | DEVELOPMENTAL BIOLOGY |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | X(Twitter) |
| 各媒体での言及数の合計 | 10 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| メダカ | TG918 hse-cre:mCherry(1) TG891 d-rR-TG(beta-actin-loxP-non-loxP-GFP) |