| RRC ID |
222
|
| Author |
Matsuda M, Sato T, Toyazaki Y, Nagahama Y, Hamaguchi S, Sakaizumi M.
|
| Title |
Oryzias curvinotus has DMY, a gene that is required for male development in the medaka, O. latipes.
|
| Journal |
Zoolog Sci
|
| Abstract |
DMY is a Y-specific DM-domain gene required for male development and appears to be the sex-determining gene in the teleost fish medaka, Oryzias latipes. Although the genomic region containing DMY appears to have originated through duplication of the DMRT1 region, it is unknown when the duplication occurred. Here we show that O. curvinotus also has the DMY gene on the Y chromosome, which is homologous to the Y chromosome of medaka, and that DMY is expressed in XY embryos. A phylogenetic tree based on the amino acid sequence including the DM-domain shows that DMY was derived from DMRT1 immediately before speciation of O. latipes and O. curvinotus.
|
| Volume |
20(2)
|
| Pages |
159-61
|
| Published |
2003-2-1
|
| DOI |
10.2108/zsj.20.159
|
| PMID |
12655179
|
| MeSH |
Amino Acid Sequence
Animals
Cloning, Molecular
Evolution, Molecular
Female
Fish Proteins / chemistry
Fish Proteins / genetics*
Gene Expression Regulation, Developmental
Male
Molecular Sequence Data
Oryzias / classification
Oryzias / embryology
Oryzias / genetics*
Phylogeny
RNA, Messenger / genetics
RNA, Messenger / metabolism
Sequence Alignment
Sex Determination Processes*
Y Chromosome / genetics*
|
| IF |
0.843
|
| Times Cited |
98
|
|
WOS Category
|
ZOOLOGY
|
| Resource |
| Medaka |
O. curvinotus |
