RRC ID 27291
Author Ando T, Nagase H, Eguchi K, Hirooka T, Nakamura T, Miyamoto K, Hirata K.
Title A novel method using cyanobacteria for ecotoxicity test of veterinary antimicrobial agents.
Journal Environ Toxicol Chem
Abstract The effect of antimicrobial agents for veterinary use on the growth of cyanobacteria was investigated by measuring minimum inhibitory concentration, medium effective concentration (EC50), and no-observed-effect concentration of seven antimicrobial agents for eight cyanobacteria. The results demonstrated that the seven antimicrobial agents, even at low concentrations, inhibited the growth of cyanobacteria. Microcystis aeruginosa and Synechococcus sp. had the highest sensitivity to the antimicrobial agents used in the present study. It is considered that the utilization of cyanobacteria would enable easy and highly sensitive assessment of the toxicity of such chemicals as antimicrobial agents. We suggest that cyanobacteria be used for ecotoxicity test in addition to the hitherto established method that uses green algae.
Volume 26(4)
Pages 601-6
Published 2007-4-1
DOI 10.1897/06-195r.1
PMID 17447543
MeSH Anti-Infective Agents / toxicity* Cyanobacteria / drug effects* Cyanobacteria / growth & development Dose-Response Relationship, Drug Microbial Sensitivity Tests No-Observed-Adverse-Effect Level Toxicity Tests / methods* Veterinary Drugs / toxicity*
IF 3.152
Times Cited 55
WOS Category TOXICOLOGY ENVIRONMENTAL SCIENCES
Resource
Algae NIES-19 NIES-44 NIES-107 NIES-23