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Species Resource
INFORMATION Human/Animal Cells A novel nonradioactive method for measuring aromatase activity using a human ovarian granulosa-like tumor cell line and an estrone ELISA.
Xenopus tropicalis Application of metamorphosis assay to a native Japanese amphibian species, Rana rugosa, for assessing effects of thyroid system affecting chemicals.
C.elegans tm1298 , tm853 C. elegans FANCD2 responds to replication stress and functions in interstrand cross-link repair.
C.elegans tm2862 Cloning and characterization of uracil-DNA glycosylase and the biological consequences of the loss of its function in the nematode Caenorhabditis elegans.
Arabidopsis / Cultured plant cells, genes rpd00105 Molecular characterization of microbial mutations induced by ion beam irradiation.
Zebrafish NA Neural defects and cardiac arrhythmia in fish larvae following embryonic exposure to 2,2',4,4'-tetrabromodiphenyl ether (PBDE 47).
Zebrafish Review Zebrafish assays for drug toxicity screening.
C.elegans tm2026 , tm2171 , tm2134 , tm1145 , tm1298 , tm2134 Caenorhabditis elegans POLQ-1 and HEL-308 function in two distinct DNA interstrand cross-link repair pathways.
Mice C57BL-p53+/- 6-mercaptopurine (6-MP) induces p53-mediated apoptosis of neural progenitor cells in the developing fetal rodent brain.
INFORMATION nbrp Cerebromalacia with epilepsy and cortical blindness in a laboratory Japanese macaque (Macaca fuscata).
DNA material pUC-ER6 Rat uterus ER cDNA (RDB01376) Effects of the phytoestrogen coumestrol on RANK-ligand-induced differentiation of osteoclasts.
DNA material pSVtsA58 ori (-) (RDB01126) Roles of MGMT and MLH1 proteins in alkylation-induced apoptosis and mutagenesis.
Zebrafish Review Zebrafish as a model vertebrate for investigating chemical toxicity.
Drosophila DGRC#105904 , DGRC#109793 Loss of RecQ5 leads to spontaneous mitotic defects and chromosomal aberrations in Drosophila melanogaster.
Mice Nrf2 knockout mouse/C57BL6J (RBRC01390) Allergic skin inflammation induced by chemical sensitizers is controlled by the transcription factor Nrf2.
Mice C57BL/6-p53 tm1Sia-Tg(gpt Delta) Low dose genotoxicity of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) in gpt delta transgenic mice.
Mice C57BL/6-p53 tm1Sia-Tg(gpt Delta) Induction of colon tumors in C57BL/6J mice fed MeIQx, IQ, or PhIP followed by dextran sulfate sodium treatment.
Rats The effect of aging on the results of the rat micronucleus assay.
Rats Relationship of interstitial edema with L-cysteine-induced sperm granulomas in the pubertal rat epididymis.
Rats Development of sperm granulomas in the epididymides of L-cysteine-treated rats.