RRC ID 2865
Author Nemoto Y, Chatani M, Inohaya K, Hiraki Y, Kudo A.
Title Expression of marker genes during otolith development in medaka.
Journal Gene Expr Patterns
Abstract Little is known about the genes and processes involved in the development of otoliths. In this study, we isolated the biomineralization-related genes otolin and chondromodulin-1 (chm1) from medaka, and examined their spatiotemporal expression pattern as well as that of two other genes also related to biomineralization, i.e., sparc/osteonectin and type II collagen (col2a), during otic development in medaka. Our results demonstrated that all the tested genes were expressed in the otic vesicle, and that chm1 was exclusively expressed in the semicircular canal of the otic vesicle.
Volume 8(2)
Pages 92-5
Published 2008-1-1
DOI 10.1016/j.modgep.2007.10.001
PII S1567-133X(07)00096-8
PMID 17981516
MeSH Animals Biomarkers* Collagen Type II / genetics Embryo, Nonmammalian Extracellular Matrix Proteins / genetics Gene Expression Regulation, Developmental* Membrane Proteins / genetics Organogenesis Oryzias / embryology* Oryzias / genetics* Osteonectin / genetics Otolithic Membrane / embryology* Semicircular Canals / embryology Semicircular Canals / metabolism
IF 0.897
Times Cited 12
WOS Category GENETICS & HEREDITY DEVELOPMENTAL BIOLOGY
Resource
Medaka Cab an inbred wild-type strain