Reference - Detail
| RRC ID | 28672 |
|---|---|
| Author | Hata M, Suzuki M, Matsumoto M, Takahashi M, Sato K, Ibe S, Sakae K. |
| Title | Cloning of a novel gene for quinolone resistance from a transferable plasmid in Shigella flexneri 2b. |
| Journal | Antimicrob Agents Chemother |
| Abstract |
A novel gene for quinolone resistance was cloned from a transferable plasmid carried by a clinical isolate of Shigella flexneri 2b that was resistant to fluoroquinolones. The plasmid conferred low-level resistance to quinolones on Escherichia coli HB101. The protein encoded by the gene showed 59% amino acid identity with Qnr. |
| Volume | 49(2) |
| Pages | 801-3 |
| Published | 2005-2-1 |
| DOI | 10.1128/AAC.49.2.801-803.2005 |
| PII | 49/2/801 |
| PMID | 15673773 |
| PMC | PMC547361 |
| MeSH | Amino Acid Sequence Anti-Bacterial Agents / pharmacology* Cloning, Molecular Drug Resistance, Bacterial Escherichia coli / drug effects Escherichia coli / genetics Microbial Sensitivity Tests Molecular Sequence Data Mutation / genetics Plasmids / genetics* Quinolones / pharmacology* Reverse Transcriptase Polymerase Chain Reaction Shigella flexneri / drug effects* Shigella flexneri / genetics* |
| IF | 4.904 |
| Times Cited | 230 |
| WOS Category | PHARMACOLOGY & PHARMACY MICROBIOLOGY |
| Resource | |
| DNA material | pBC-H2.6 (RDB05463) pBC-H8.4 (RDB05464) |