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  • Search Condition : Filter (MeSH = Mutation / genetics)
Species Resource
Rats F344.CVD-Unc5ccvd/Kyo(strainID=153) Rat neurological mutations cerebellar vermis defect and hobble are caused by mutations in the netrin-1 receptor gene Unc5h3.
Cellular slime molds Overexpression of sphingosine-1-phosphate lyase or inhibition of sphingosine kinase in Dictyostelium discoideum results in a selective increase in sensitivity to platinum-based chemotherapy drugs.
Cellular slime molds S00342 RasC plays a role in transduction of temporal gradient information in the cyclic-AMP wave of Dictyostelium discoideum.
Cellular slime molds Genome-wide expression analyses of gene regulation during early development of Dictyostelium discoideum.
Medaka RS274 , RS275 Co-option of Sox3 as the male-determining factor on the Y chromosome in the fish Oryzias dancena.
DNA material pKU1 (RDB08559) , pKU105 (RDB08570) , pKU106 (RDB08571) , pKU108 (RDB08572) , pKU121 (RDB08573) , pKU131 (RDB08574) , pKU158 (YCpTAT23K>R-3HA) (RDB08575) , pKU41 (RDB08560) , pKU46 (YCpTAT2?3HA) (RDB08561) , pKU51 (RDB08562) , ... Ergosterol is required for targeting of tryptophan permease to the yeast plasma membrane.
Lotus / Glycine L. japonicus EMS mutant Lotus japonicus nodulation is photomorphogenetically controlled by sensing the red/far red (R/FR) ratio through jasmonic acid (JA) signaling.
Lotus / Glycine pUB-GW-GFP Legume pectate lyase required for root infection by rhizobia.
Drosophila Thioredoxin suppresses Parkin-associated endothelin receptor-like receptor-induced neurotoxicity and extends longevity in Drosophila.
Drosophila Loss of Trx-2 enhances oxidative stress-dependent phenotypes in Drosophila.
DNA material Oct3pluc BstXI-NcoI (RDB10752) , Oct3pluc PstI-NcoI (RDB10753) , Oct3pluc BamHI-NcoI (RDB10754) , pGL3b Hind/NcoI (-1938/-1) (RDB10986). Oct-3/4 and Sox2 regulate Oct-3/4 gene in embryonic stem cells.
Drosophila bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila.
Tropical clawed frog Ivory Coast line Generation of albino Xenopus tropicalis using zinc-finger nucleases.
Yeast S. pombe strains The CENP-A N-tail confers epigenetic stability to centromeres via the CENP-T branch of the CCAN in fission yeast.
Drosophila Calpain A modulates Toll responses by limited Cactus/IκB proteolysis.
Drosophila Pri peptides are mediators of ecdysone for the temporal control of development.
DNA material BS-KS HOIL-1 (RDB04183) Identification of the ubiquitin-protein ligase that recognizes oxidized IRP2.
Medaka TG1043 , TG1044 The PAR complex controls the spatiotemporal dynamics of F-actin and the MTOC in directionally migrating leukocytes.
Medaka MT374 (hirame) , MT364 (fukuwarai) , MT830 (OK-Cab) , WS339 (K-Kaga) YAP is essential for tissue tension to ensure vertebrate 3D body shape.
Drosophila DRONC coordinates cell death and compensatory proliferation.