RRC ID 28822
Author Watanabe MF, Oishi S, Harda K, Matsuura K, Kawai H, Suzuki M.
Title Toxins contained in Microcystis species of cyanobacteria (blue-green algae).
Journal Toxicon
Abstract Cyclic peptide toxins were analyzed for three Microcystis species (M. aeruginosa, M. viridis and M. wesenbergii) using an ODS-silica gel cartridge and high performance liquid chromatography with ODS-silica gel. On strain of M. aeruginosa contained a high amount of microcystin (cyanoginosin) YR and a lesser amount of LR. Three toxins, microcystin-RR, -YR and -LR, were detected in two strains of M. aeruginosa and four of M. viridis. The main component of the toxins of these strains was microcystin-RR. M. wesenbergii showed no peak in the area where the three toxins were obtained in other Microcytisis species by HPLC analysis. LD50 values of the purified toxins of YR and LR were similar, while a lower toxicity was estimated for RR. This explains the relatively weak toxicity of M. viridis whose main component is microcystin-RR.
Volume 26(11)
Pages 1017-25
Published 1988-1-1
DOI 10.1016/0041-0101(88)90200-0
PMID 3149802
MeSH Animals Bacterial Toxins* Chromatography, High Pressure Liquid Cyanobacteria Toxins Lethal Dose 50 Magnetic Resonance Spectroscopy Marine Toxins / isolation & purification Marine Toxins / toxicity* Mass Spectrometry Mice Microcystins Microcystis / analysis*
IF 2.201
Times Cited 112
Algae NIES-103 NIES-112 NIES-1059 NIES-1084 NIES-3349