RRC ID 2928
Author Girish Kumar CP, Hanafy AM, Katsu M, Mikami Y, Menon T.
Title Molecular analysis and susceptibility profiling of Candida albicans isolates from immunocompromised patients in South India.
Journal Mycopathologia
Abstract The genetic diversity and in vitro antifungal susceptibility profiles of 55 Candida albicans from immunocompromised patients were studied. PCR based analysis of the transposable intron in the 25S rDNA revealed 39 genotype A, 4 genotype B and 12 genotype C isolates. Serotype analysis categorized 52 isolates as serotype A and 3 as serotype B. All strains were susceptible to micafungin, 5-flucytosine and miconazole, whereas resistance against amphotericin B (3.6%), fluconazole (3.6%), itraconazole (7.3%) and voriconazole (5.5%) was observed. No association was seen between antifungal resistance and genotype/serotype status.
Volume 161(3)
Pages 153-9
Published 2006-3-1
DOI 10.1007/s11046-005-9210-6
PMID 16482387
MeSH Antifungal Agents / pharmacology* Candida albicans / drug effects* Candida albicans / genetics* Candida albicans / isolation & purification Candidiasis / immunology* Candidiasis / microbiology* DNA, Fungal / chemistry DNA, Fungal / genetics Genetic Variation Genotype Humans Immunocompromised Host* India Microbial Sensitivity Tests Polymerase Chain Reaction RNA, Ribosomal / chemistry RNA, Ribosomal / genetics Serotyping
IF 2.452
Times Cited 10
Pathogenic microorganisms IFM 40213 IFM 40214 IFM 48313 IFM 52112