Reference - Detail
| RRC ID | 29768 |
|---|---|
| Author | White BJ, Hochhauser SJ, Cintron NM, Weiss B. |
| Title | Genetic mapping of xthA, the structural gene for exonuclease III in Escherichia coli K-12. |
| Journal | J Bacteriol |
| Abstract |
The genes xthA, pncA, and pabB were ordered relative to others by two- and three-factor transductional crosses with bacteriophage P1. The genes studied span 2 min (2%) of the genetic map of Escherichia coli K-12 in the clockwise sequence pheS-pfkB-xthA-pncA-gap-pabB-fadD. Eleven independently derived xth mutations were examined; all were known to affect exonuclease III and its associated endonuclease II activity, and all were mapped in the xthA region. pncA mutations were found to confer resistance to 6-aminonicotinamide, whereas some pheS mutations are known to specify resistance to p-fluorphenylalanine. xth mutations were readily transferred into other strains by selecting for these co-transducible drug resistance markers. |
| Volume | 126(3) |
| Pages | 1082-8 |
| Published | 1976-6-1 |
| DOI | 10.1128/jb.126.3.1082-1088.1976 |
| PMID | 780339 |
| PMC | PMC233128 |
| MeSH | 6-Aminonicotinamide / pharmacology Chromosome Mapping Deoxyribonucleases / biosynthesis Drug Resistance, Microbial Endonucleases / metabolism Escherichia coli / drug effects Escherichia coli / enzymology* Exonucleases / biosynthesis* Genes* Transduction, Genetic p-Fluorophenylalanine / pharmacology |
| IF | 3.006 |
| Altmetric score |
オルトメトリクス指標項目
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| The most frequently cited source | Patent(IFI CLAIMS) |
| Total number of mentions | 2 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| Prokaryotes E. coli | ME8644 |