| RRC ID |
29791
|
| Author |
Polarek JW, Williams G, Epstein W.
|
| Title |
The products of the kdpDE operon are required for expression of the Kdp ATPase of Escherichia coli.
|
| Journal |
J Bacteriol
|
| Abstract |
The expression of the Kdp system for K+ uptake in Escherichia coli requires the products of two genes, kdpD and kdpE. These genes constitute an operon adjacent to the kdpABC operon that encodes the three membrane protein subunits of Kdp. Both operons are transcribed in the same direction and overlap; the kdpDE promoter is in kdpC, the last gene of the kdpABC operon. Transcription of the kdpDE operon is at a low level when Kdp is not expressed; transcription increases about 10-fold when kdpABC is turned on, indicating significant read-through of the kdpDE operon by transcripts beginning at the promoter of kdpABC operon. The proximal region of the kdpD gene is the site of most mutations that lead to constitutive expression of the kdpABC operon.
|
| Volume |
174(7)
|
| Pages |
2145-51
|
| Published |
1992-4-1
|
| DOI |
10.1128/jb.174.7.2145-2151.1992
|
| PMID |
1532387
|
| PMC |
PMC205832
|
| MeSH |
Adenosine Triphosphatases / genetics*
Amino Acid Sequence
Bacterial Proteins / genetics
Base Sequence
Biological Transport, Active
Cation Transport Proteins
Chromosome Mapping
Cloning, Molecular
DNA, Bacterial / genetics
Escherichia coli / enzymology
Escherichia coli / genetics*
Gene Expression Regulation, Bacterial*
Genes, Bacterial*
Genes, Regulator
Molecular Sequence Data
Operon
Potassium / metabolism*
Promoter Regions, Genetic
Restriction Mapping
Transcription, Genetic
|
| IF |
3.006
|
| Times Cited |
90
|
|
WOS Category
|
MICROBIOLOGY
|
| Resource |
| Prokaryotes E. coli |
ME9047 |
