RRC ID 29791
著者 Polarek JW, Williams G, Epstein W.
タイトル The products of the kdpDE operon are required for expression of the Kdp ATPase of Escherichia coli.
ジャーナル J Bacteriol
Abstract The expression of the Kdp system for K+ uptake in Escherichia coli requires the products of two genes, kdpD and kdpE. These genes constitute an operon adjacent to the kdpABC operon that encodes the three membrane protein subunits of Kdp. Both operons are transcribed in the same direction and overlap; the kdpDE promoter is in kdpC, the last gene of the kdpABC operon. Transcription of the kdpDE operon is at a low level when Kdp is not expressed; transcription increases about 10-fold when kdpABC is turned on, indicating significant read-through of the kdpDE operon by transcripts beginning at the promoter of kdpABC operon. The proximal region of the kdpD gene is the site of most mutations that lead to constitutive expression of the kdpABC operon.
巻・号 174(7)
ページ 2145-51
公開日 1992-4-1
DOI 10.1128/jb.174.7.2145-2151.1992
PMID 1532387
PMC PMC205832
MeSH Adenosine Triphosphatases / genetics* Amino Acid Sequence Bacterial Proteins / genetics Base Sequence Biological Transport, Active Cation Transport Proteins Chromosome Mapping Cloning, Molecular DNA, Bacterial / genetics Escherichia coli / enzymology Escherichia coli / genetics* Gene Expression Regulation, Bacterial* Genes, Bacterial* Genes, Regulator Molecular Sequence Data Operon Potassium / metabolism* Promoter Regions, Genetic Restriction Mapping Transcription, Genetic
IF 3.006
引用数 90
WOS 分野 MICROBIOLOGY
リソース情報
原核生物(大腸菌) ME9047