RRC ID 29856
Author Plamann MD, Stauffer GV.
Title Characterization of a cis-acting regulatory mutation that maps at the distal end of the Escherichia coli glyA gene.
Journal J Bacteriol
Abstract We have isolated a phage Mu cts-generated glyA mutant with only 30% of the normal level of serine hydroxymethyltransferase activity. Genetic and physical mapping studies show that Mu cts has inserted between the end of the glyA structural gene and its proposed transcription termination site. The mutation is cis acting and shows that sequences distal to the glyA structural gene play an important role in the expression of this gene.
Volume 161(2)
Pages 650-4
Published 1985-2-1
DOI 10.1128/jb.161.2.650-654.1985
PMID 3881406
PMC PMC214932
MeSH Aminomethyltransferase Base Sequence Chromosome Mapping* DNA, Bacterial / analysis Escherichia coli / genetics* Glycine Hydroxymethyltransferase / genetics* Hydroxymethyl and Formyl Transferases* Mutation* Transferases / genetics*
IF 3.006
Times Cited 21
WOS Category MICROBIOLOGY
Resource
Prokaryotes E. coli ME8367