RRC ID 29859
Author Elvin CM, Hardy CM, Rosenberg H.
Title Pi exchange mediated by the GlpT-dependent sn-glycerol-3-phosphate transport system in Escherichia coli.
Journal J Bacteriol
Abstract The GlpT system for sn-glycerol-3-phosphate transport in Escherichia coli is shown to catalyze a rapid efflux of Pi from the internal phosphate pools in response to externally added Pi or glycerol-3-phosphate. A glpR mutation, which results in constitutive expression of the GlpT system, is responsible for this rapid Pi efflux and the arsenate sensitivity of several laboratory strains, including the popular strain C600. Glucose and other phosphotransferase system sugars inhibit Pi efflux by repressing glpT expression.
Volume 161(3)
Pages 1054-8
Published 1985-3-1
DOI 10.1128/JB.161.3.1054-1058.1985
PMID 3882662
PMC PMC215006
MeSH Arsenates / toxicity Biological Transport, Active Cell Membrane / metabolism Chromosome Mapping Escherichia coli / metabolism* Genes, Bacterial Glycerophosphates / metabolism* Operon Phosphates / metabolism*
IF 3.234
Times Cited 65
Prokaryotes E. coli ME8362 ME8363 ME8364