RRC ID 29869
Author Hrebenda J, Heleszko H, Brzostek K, Bielecki J.
Title Mutation affecting resistance of Escherichia coli K12 to nalidixic acid.
Journal J Gen Microbiol
Abstract A new mutation, nalD, determining resistance of Escherichia coli to nalidixic acid (NAL) is reported. The nalD mutant described is resistant to NAL at 37 degrees C but sensitive at 30 degrees C. It is defective in penetration of NAL and glycerol through the outer membrane at 37 degrees C. The nalD mutation is located half-way between 89 and 89.5 min on the E. coli genetic map.
Volume 131(9)
Pages 2285-92
Published 1985-9-1
DOI 10.1099/00221287-131-9-2285
PMID 3906038
MeSH Biological Transport Cell Membrane Permeability / drug effects Chromosome Mapping Conjugation, Genetic DNA, Bacterial / biosynthesis Drug Resistance, Microbial Escherichia coli / drug effects* Escherichia coli / genetics Escherichia coli / growth & development Mutation* Nalidixic Acid / metabolism Nalidixic Acid / pharmacology*
Times Cited 28
Prokaryotes E. coli ME8567