論文 - 詳細
| RRC ID | 29869 |
|---|---|
| 著者 | Hrebenda J, Heleszko H, Brzostek K, Bielecki J. |
| タイトル | Mutation affecting resistance of Escherichia coli K12 to nalidixic acid. |
| ジャーナル | J Gen Microbiol |
| Abstract |
A new mutation, nalD, determining resistance of Escherichia coli to nalidixic acid (NAL) is reported. The nalD mutant described is resistant to NAL at 37 degrees C but sensitive at 30 degrees C. It is defective in penetration of NAL and glycerol through the outer membrane at 37 degrees C. The nalD mutation is located half-way between 89 and 89.5 min on the E. coli genetic map. |
| 巻・号 | 131(9) |
| ページ | 2285-92 |
| 公開日 | 1985-9-1 |
| DOI | 10.1099/00221287-131-9-2285 |
| PMID | 3906038 |
| MeSH | Biological Transport Cell Membrane Permeability / drug effects Chromosome Mapping Conjugation, Genetic DNA, Bacterial / biosynthesis Drug Resistance, Microbial Escherichia coli / drug effects* Escherichia coli / genetics Escherichia coli / growth & development Mutation* Nalidixic Acid / metabolism Nalidixic Acid / pharmacology* |
| 引用数 | 28 |
| WOS 分野 | MICROBIOLOGY |
| リソース情報 | |
| 原核生物(大腸菌) | ME8567 |