論文 - 詳細
| RRC ID | 30041 |
|---|---|
| 著者 | Hill CW, Harnish BW. |
| タイトル | Inversions between ribosomal RNA genes of Escherichia coli. |
| ジャーナル | Proc Natl Acad Sci U S A |
| Abstract |
It might be anticipated that the presence of redundant but oppositely oriented sequences in a chromosome could allow inversion of the intervening material through homologous recombination. For example, the ribosomal RNA gene rrnD of Escherichia coli has the opposite orientation fro rrnB and rrnE and is separated from these genes by roughly 20% of the chromosome. Starting with a derivative of Cavalli Hfr, we have constructed mutants that have an inversion of the segment between rrnD and either rrnB or rrnE. These mutants are generally quite viable but do exhibit a slight reduction in growth rate relative to the parental strain. A major line of laboratory E. coli, W3110 and its derivatives, also has an inversion between rrnD and rrnE, probably created directly by a recombinational event between these highly homologous genes. |
| 巻・号 | 78(11) |
| ページ | 7069-72 |
| 公開日 | 1981-11-1 |
| DOI | 10.1073/pnas.78.11.7069 |
| PMID | 6273909 |
| PMC | PMC349196 |
| MeSH | Crosses, Genetic DNA Restriction Enzymes Escherichia coli / genetics* Mutation Nucleic Acid Hybridization RNA, Ribosomal / genetics* Recombination, Genetic Suppression, Genetic* |
| IF | 9.412 |
| 引用数 | 230 |
| WOS 分野 | BIOLOGY |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | Patent(IFI CLAIMS) |
| 各媒体での言及数の合計 | 7 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| 原核生物(大腸菌) | ME6253 |